Abakavir-AVS – antiviral means, active concerning HIV.
Dosage form – tablets, film coated: a round biconvex form, brownish-yellow color, at a break two layers from which a tablet kernel – from color, white to white with a yellow shade are visible (10 pieces in a blister strip packaging, in a cardboard pack of 6 packagings; on 60 pieces in polymeric banks or bottles, in a cardboard pack of 1 bank or a bottle).
Abakavira-AVS active ingredient – an abakavira sulfate, in 1 tablet – 0,351 g that is equivalent to 0,3 g of an abakavir.
Auxiliary components: silicon dioxide colloid (aerosil), cellulose microcrystallic, magnesium stearate, sodium carboxymethylstarch.
Structure of a film cover: опадрай II 85F220031 yellow (titanium dioxide, polyvinyl alcohol, talc, macrogoal 4000, dye ferrous oxide yellow).
Use of Abakavira-AVS is shown as a part of a combination therapy of HIV infection.
With care should apply the patients inclined to developing of coronary heart disease, and also at arterial hypertension, a diabetes mellitus, a dislipidemiya, smoking.
Expediency of purpose of drug during pregnancy is defined by the doctor, having weighed the expected effect of therapy for mother and potential threat for a fruit.
Pill is taken inside.
The recommended dosing:
Against the background of use of an abakavir, is more often during the first 6 weeks of treatment, emergence of symptoms of hypersensitivity is possible, in this case drug should be cancelled.
There is a risk of development of fatty dystrophy of a liver, a hepatomegalia, lactoacidosis, including with fatal effects (more often women are subject to the specified complications).
Treat symptoms of lactoacidosis: a loss of appetite, the general weakness, bystry loss of weight of not clear etiology, disturbance from respiratory system (an asthma, a tachypnea) and digestive tract.
In case of clinical signs or disturbance of the laboratory indicators confirming lactoacidosis or a hepatotoxic (at a hepatomegalia and fatty dystrophy of a liver even without the expressed increase in activity of aminotransferases), reception of tablets needs to be stopped.
Use of Abakavira-AVS should be accompanied with regular clinical inspection of patients regarding redistribution of a hypodermic fatty tissue as the anti-retrovirus combination therapy can cause development of a syndrome of a lipodystrophy. At disturbance of lipidic exchange (level of concentration of lipids and glucose in blood serum) to the patient appoint additional treatment.
In the presence of asymptomatic opportunistic infections (or oligosymptomatic) with the expressed immunodeficiency at the time of the beginning of the combined anti-retrovirus therapy treatment can cause strengthening of symptoms of an infection in HIV-positive patients and lead to serious consequences. Characteristic pathologies are the Cytomegaloviral retinitis, a focal or generalized mikobakterialny infection, the pneumonia caused by Pneumocystis jirovecii.
Because of big risk of development of complications of HIV infection or opportunistic infections during reception of Abakavira-AVS patients need constant observation of the doctor for timely purpose of adequate therapy.
The possibility of simultaneous use of other medicines during treatment abakaviry is defined by the attending physician.
To store in the place, unavailable to children, at a temperature not above 25 °C.
Period of validity – 2 years.
To tell even the shortest and simple words, we involve 72 muscles.
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