Aertal

Aertal – the non-steroidal anti-inflammatory drug applied to removal of an inflammation, heat, pain at rheumatism, reduction of constraint of joints in the mornings and their swellings.

Form of release and structure

Dosage forms of Aertal:

• Tablets, film coated: biconvex, round (diameter about 8 mm), covered with a white film cover, with a unilateral engraving "And" (in blisters on 10 pieces, in a pack cardboard on 1, 2, 3, 4, 6 or 9 blisters);
• Powder for production of suspension for oral administration: color white with a cream shade or white (in three-layered packages, in a pack of cardboard 20 packages);
External
• use cream: homogeneous substance of white color (in aluminum tubas on 60 g, in a pack a cardboard 1 tuba).

Active agent of all forms of release – ацеклофенак.

In 1 tablet:

• Active agent: ацеклофенак – 100 mg;
• Excipients: croscarmellose sodium, cellulose microcrystallic, glyceryl distearate (type I), povidone.

In 1 package:

• Active agent: ацеклофенак – 100 mg;
• Auxiliary components: sorbitol, sodium saccharinate, aspartame, silicon dioxide colloid, gipromelloza, titanium dioxide, fragrances milk, caramel and cream.

In 1 g of cream:

• Atseklofenak (100% micronized) – 15 mg;
• Excipients: methylparahydroxybenzoate, пропилпарагидроксибензоат, liquid paraffin, wax emulsion, water.

Indications to use

Aertal's use is recommended for removal of pains and reduction of an inflammation at such diseases as:

• Lumbago;
• Humeroscapular periarthritis;
• Rheumatism of soft tissues;
• Osteoarthrosis;
• Ankylosing spondylitis;
• Pseudorheumatism;
• Other diseases of a musculoskeletal system.

Also Aertal successfully use for removal of a dentagra.

External use cream suppresses edematization and an erythema irrespective of an inflammation etiology, makes local analgeziruyushchy and antiinflammatory impact.

Contraindications

• Ulcer, erosion and bleedings from a GIT;
• Bronchospasm;
• Small tortoiseshell;
• The rhinitis caused by reception of aspirin and other nonsteroid drugs;
• The expressed liver failure;
• Hemopoiesis process disturbances;
• Hyperpotassemia;
• Breastfeeding, pregnancy;
• Hypersensitivity to active and to excipients of drug.

Aertal in any forms of release do not appoint to children up to 18 years.

With caution patients with diseases of kidneys, a liver, a GIT, bronchial asthma, supertension, ischemia, a chronic liver and/or renal failure, diabetes, diseases of peripheral arteries, at advanced age have to take drug, at an alcohol abuse, nicotine, at long reception of non-steroidal anti-inflammatory drugs.

Contraindications for use of drug in the form of cream is disturbance of integrity of integuments in the place of alleged drawing.

Route of administration and dosage

Tablets Aertal cannot be chewed and crushed. The necessary therapeutic dosage is appointed by the doctor, it averages 100 mg – 2 tablets a day which accept in 2 receptions (in the morning and in the evening).

Powder Aertal for intake in need of reduction of expressiveness of a pain syndrome can be applied to production of suspension once. For therapy of diseases appoint 1 bag in the morning and 1 bag in the evening. It is necessary to prepare suspension so: to dissolve contents of a package in 40-60 ml of water, it is necessary to drink the received mix at once.

Cream Aertal is used only for external use, it is not necessary to apply cream under compressing bandages.

Cream is rubbed by the easy movements on area of possible defeat 3 times a day in quantity at the rate of 1,5-2,0 g (about a size of a pea) on 5-7 ^cm2 of a body surface.

Side effects

Aertal's use is capable to exert a negative impact on various systems of an organism:

• Alimentary system: vomiting, diarrhea, epigastric pains, gripes, meteorism, lock, nausea, cankers and erosion, stomatitis, hepatitis, pancreatitis;
• Central and peripheral nervous system: perhaps – sleep disorders, irritability, dizziness, a depression, paresthesia, вертиго, uneasiness, a tremor, a disorientation, meningitis, disturbances of memory, sight, sensitivity, taste;
• Others: allergy, puffiness, insufficiency of function of kidneys, nephrite, proteinuria, hamaturia, leukopenia, agranulocytosis, anemia, thrombocytopenia, hypertensia, heart failure, ischemia.

Special instructions

Aertal reduces efficiency of drugs against supertension, diuretics. In combination with kaliysberegayushchy diuretics drug can cause a hyperpotassemia or a hyperglycemia.

The risk of development of side effects increases at simultaneous use of Aertal with glucocorticosteroids or other nonsteroid drugs. Besides, drug can increase nephrotoxicity of cyclosporine.

It is necessary to show care to patients with renal, liver, heart failure, and also with other diseases assuming development of hypostases. Reception of NPVS at this category of patients can lead to deterioration in renal excretion and developing of hypostases.

It is necessary to be careful at Aertal's appointment along with diuretic drugs, at the increased risk of development of a hypovolemia, and also to elderly patients.

Patients with intolerance of fructose cannot appoint ацеклофенак in powder as it contains 2640 mg of sorbitol that can provoke a gastric disturbance or diarrhea.

With a fenilketonuriya it is important to patients to consider that in each bag of powder – 5,61 mg of phenylalanine.

Patients should not manage difficult mechanisms and vehicles which have at reception of an atseklofenak of dizziness, feeling of weakness, other disturbances from the central nervous system.

Analogs

Direct analog of Aertal – Asinak.

Drugs of one pharmpodgruppa, relatives on the influence mechanism: Adolor, Bioran, Voltarenum, Diklak, Diklogen, Diclofenac, Dolak, Dolomin, Indometatsin, Ketalgin, Ketanov, Naklofen, Ortophenum, Panoksen, Flotak, Hondrofen, etc.

Terms and storage conditions

To store in the place unavailable to children:

• Tablets: at a temperature up to 25 °C, a period of validity – 3 years;
• Powder: at a temperature up to 30 °C, a period of validity – 4 years;
• Cream: at a temperature up to 25 °C, a period of validity – 2 years.