Azaphenum
Application instruction:
Azaphenum is a medicine which possesses the sedative and calming action.
Form of release and structure
Azaphenum concerns to group of tricyclic antidepressants. Has sedative properties.
Is issued in the form of the tablets containing 25 mg of active agent – Pipofezinum of dihydrochloride of the monohydrate which is in a matrix carrier.
Excipients:
- Potato starch;
- Silicon dioxide colloid (aerosil);
- Cellulose microcrystallic;
- Lactoses monohydrate;
- Povidone (polyvinylpirrolidone low-molecular medical);
- Magnesium stearate.
Indications to use
Efficiency of Pipofezinum is based on stopping of symptoms of a depression therefore indications to use of Azaphenum are depressions of various origin, including:
- Endogenous;
- Exogenous;
- Alcoholic;
- Senile.
Besides, drug is used for treatment of the following states:
- Depressions against the background of chronic somatic diseases;
- Alarming and depressive syndromes;
- Depressive phase at a maniac-depressive syndrome;
- Asthenoneurotic syndromes.
First of all after an initiation of treatment there occurs improvement of mood after this uneasiness and block disappears.
Contraindications
According to the instruction to Azaphenum, tablets are contraindicated at:
- Hypersensitivity to Pipofezinum;
- Renal failure;
- Liver failure;
- Heart attack;
- States after a stroke;
- Heart failure;
- Diabetes mellitus;
- Infectious diseases.
Use at pregnancy and feeding by a breast, and also in parallel with reception of MAO inhibitors is forbidden. At children's age it is possible to accept antidepressant only to destination doctors and under fixed medical observation. It is explained by the insufficient number of data on safety of use of Azaphenum by children.
Route of administration and dosage
Pill is taken inside, washing down with a small amount of liquid. The initial dose makes 25-50 mg a day for two receptions. In need of and in the absence of negative effects increase in a dose up to 200 mg a day which need to be taken for two or three times is possible. The maximum quantity of drug makes 500 mg a day.
After stabilization of a state the maintenance dose which makes about 25-75 mg a day is recommended. Treatment duration – from one month to one year.
Azaphenum does not exert a negative impact on heart. Completely and for the short period it is soaked up from a stomach and intestines.
Side effects
Drug is rather well transferred, does not cause drowsiness and does not strengthen sensation of fear though some side effects nevertheless can be present.
According to the instruction to Azaphenum, emergence of a headache, allergic reactions, vomitings or nausea, dizzinesses is possible. In these cases the dose decline is recommended.
Special instructions
During administration of drug alcohol intake is forbidden.
From time to time it is necessary to exercise control of functioning of a liver and kidneys.
During treatment by Azaphenum patients need to refrain from occupations at which special attention or bystry psychomotor reactions, for example, from driving is required.
Analogs
Pipofezinum is not a part of other drugs.
Azaphenum analogs on the mechanism of action are:
- Alventa;
- Befol;
- Velaksin;
- Deprim;
- Koaksil;
- Mirtazonal;
- Normazidol;
- Pyrazidolum;
- Tetrindol;
- Esprital and other medicines.
Terms and storage conditions
To store in the dry, dark place, at air temperature not above 25 °C. A period of validity – 3 years.
Name of drug
Price
Drugstore
Azaphenum тбл 25 mg No. 50 *, Makiz-Pharma of Ltd company
187 rub.
Network of the Moscow drugstores of IFCAzaphenum тбл 25 mg No. 250 **, Makiz-Pharma of Ltd company
672 rub.
Network of the Moscow drugstores of IFCStomatologists appeared relatively recently. In the 19th century to pull out painful teeth belonged to duties of the ordinary hairdresser.
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