Klion-d

Klion-d – the combined synthetic drug with antifungal, antibacterial and antiprotozoan action applied in gynecology.

Pharmacological action

Klion-d active ingredients have protivoprotozoynyy, antibacterial and antifungal effect.

Drug is active in the relation:

• Giardia lamblia;
• Fusobacterium spp.;
• Prevotella spp.;
• Eubacterium spp.;
• Gardnerella vaginalis;
• Peptostreptococcus spp.;
• Bacteroides spp.;
• Peptococcus spp.;
• Entamoeba histolytica;
• Trichomonas vaginalis;
• Clostridium spp.;

Also Klion-d has antifungal effect concerning barmy mushrooms and dermatophytes, generally concerning Candida albicans.

According to Klion-d it is transferred well and does not change players of normal microflora and acidity of a vagina.

Release form

Klion-d release in a look:

• Tablets, each tablet contains 250 mg of metronidazole, on 20 tablets in packaging;
• Infusion solution in a bottle of 100 ml;
• Oval biconvex vulval tablets with the pointed end and an engraving "100" (candles of Klion-d or Klion-d 100), each tablet contains 100 mg of metronidazole and Miconazolum of nitrate. On 10 candles in packaging.

Indications to use of Klion-d

According to the instruction of Klion-d apply to treatment of the infectious and inflammatory diseases caused by fuzobakteriya, clostridiums, bacteroids and anaerobic cocci:

• Abscesses in a small pelvis;
• Sepsis;
• Osteomyelitis;
• Endometritis;
• Gas gangrene;
• Peritonitis;
• Meningitis.

Also Klion-d apply as prevention of postoperative infectious complications which anaerobic flora – bacteroids and anaerobic streptococci can cause, especially after operations on bodies of a small pelvis and abdominal cavity.

Klion-d 100 apply as topical treatment of vaginit of the mixed etiology which at the same time cause Trichomonas spp. and Candida spp.

Contraindications

According to the instruction of Klion-d it is contraindicated at:

• Leukopenias;
• Liver failure;
• Hypersensitivity to the Klion-d components and other azoles;
• Organic lesions of the central nervous system, including epilepsy.

Klion-D at pregnancy in the first and second trimesters, at children's age up to 12 years and in the period of a lactation it is contraindicated to use in any dosage forms.

According to the instruction of Klion-d appoint with care at disturbances of microcirculation and a diabetes mellitus. At use of Klion-d it is not necessary to take alcohol.

Application instruction of Klion-d

According to the instruction of Klion-d in the form of tablets accept:

• At trikhomonadoza – on one twice a day, in the morning and in the evening, for 10 days. Use of 8 tablets as single dose is possible in the evening;
• At lamblioza – for a week 2 times a day on 2 tablets;
• At amebiases – three times a day on 2 tablets for 7-10 days.

Infusion solution is applied intravenously and kapelno a course of 7 days. At improvement of a state pass to oral administration of Klion-d 3 times a day 400 mg.

Candles of Klion-d apply intravaginalno, previously having moistened a tablet with water. Usually the course of treatment of Klion-d 100 proceeds 10 days with concomitant oral administration of the drugs containing metronidazole (Klion-d).

During use of candles of Klion-d it is recommended to abstain from sexual contacts. Also simultaneous treatment of the sexual partner of Klion-d for intake is recommended irrespective of whether the disease is shown at it.

At pregnancy of Klion-d it is allowed for use only according to strict indications in the third trimester. Usually drug is appointed at vagina candidiasis (milkwoman).

According to Klion-d at pregnancy it is safest and effective at use on 36-37 week.

Side effects

At use of Klion-d 100 according to the instruction there can be various side effects – an itch, pain, irritation and burning of a mucous membrane of a vagina. Use of candles of Klion-d can also cause white, dense, mucous allocations from an inodorous vagina and a burning sensation or irritation of a penis in the partner.

According to Klion-d at oral administration can cause vomiting, a loss of appetite, nausea, a headache, change of flavoring feelings, dizziness, metal smack in a mouth, a lock, abdominal pains and diarrhea.

Allergic reactions in the form of an itch, rashes and urticarias of Klion-d according to reviews causes seldom.

Storage conditions

Klion-d it is released according to the medical recipe. A drug period of storage – 5 years.