Boven's disease
Contents:
Description:
Boven's disease is also cheshuychasto-cellular carcinoma of "in situ". This type of a carcinoma cutaneum forms on the surface of skin. While "invasive" cheshuychasto-cellular carcinomas can grow in inside and extend to internals.
Symptoms of the Disease of Boven:
New growths are usually single, is more rare multiple in the form of the monetovidny or blyashechny element of rounded shape having slow peripheral growth. Quite often initial element is located on an erythematic background. The center of the center sinks down a little and has poorly expressed borodavchatost. Color of a plaque almost normal or copper-pink. It is localized on skin of buttocks, trunks, extremities, sometimes in an oral cavity, it is rare on palms, soles, a neck of uterus. During removal it is central the located crusts the erosion later replaced by a hem is bared. The hyperadenosis is observed seldom.
Histologically: lengthening and a thickening of epidermal shoots at the uneven size of kernels and some vacuolation of cells. In a malpigiyevy layer of epidermis the keratosic cells and accumulation of a keratin. Diskeratozny round cells, clusters of numerous kernels in cells with an atypical mitosis are characteristic. It is necessary to differentiate with a vulgar wart, horn it is deprived, tertiary syphilides and sarcoids.
Type of integuments at Boven's disease
Boven etiologies:
The pathogeny of a bowenoid papulez is connected with disturbance of an immune response and hormonal factors.
Treatment of the Disease of Boven:
Removal surgical or by means of electrothermic coagulation with the subsequent γ-therapy, a roentgenotherapy at a voltage of generation of 100 — 180 kV and a total dose of 6000 — 7000 Rubles. Use of 5% of ftoruratsilovy ointment is quite often successful in the beginning. Patients have to stay on the dispensary registry in oncological institutions.
