Producer: JSC Pharmak Ukraine
Code of automatic telephone exchange: R01AA07
Release form: Liquid dosage forms. Drops.
General characteristics. Structure:
Active ingredient: xylomethazoline;
1 ml of drug contains hydrochloride xylomethazolinum in terms of 100% substance of 0,5 mg or 1 mg;
excipients: sodium hydrophosphate, dodecahydrate; sodium dihydrophosphate, dihydrate; sorbite (Е 420); decamethoxynum; dinatrium эдетат, water for injections.
Фармазолин® belongs to non-selective alpha адреномиметикам which locally narrow vessels of a mucous membrane and reduce expressiveness of processes of an inflammation. When drawing has antiedematous effect on a mucous membrane of a nose, reduces a hyperemia and exudation that promotes simplification of nasal breath, reduction of a blood-groove in venous sine.
Drug has preferential local effect, is soaked up through mucous membranes at usual use in insignificant quantity. Effect of drug begins in 5–10 minutes and continues within 5-6 hours.
Indications to use:
Relief of symptoms of acute rhinitises of various etiology, sinusitis.
At diagnostic interventions (rinoskopiya).
Route of administration and doses:
When using a bottle polyethylene before the first use as much as possible screw up a cap. At the same time the thorn which is on the cap interior punctures an opening. The cap is unscrewed, removed and, slightly pressing on the bottle case, solution is dug in in a nose.
When using a bottle of disclosure, polyethylene with control, just before use the bottle needs to be taken in a palm to warm up it to body temperature. After an instillation it is dense to screw up a cap.
Solution of 0,05%
To children from 3 months to 6 years dig in 1-2 drops in each nasal course 1-2 times a day (no more than 3 times a day). Duration of treatment depends on the course of a disease and makes no more than 10 days in a row.
Solution of 0,1%
To adults and children 6 years are more senior dig in 2-3 drops in each nasal course 3-4 times a day.
The course of treatment depends on the course of a disease and should not exceed 10 days in a row. After the termination of a course of treatment it is possible to appoint drug again only in several days.
It is reasonable to appoint Фармазолин® 0,05% to patients who did not use vasoconstrictive drugs earlier, and to children up to 6 years. In case of insufficient efficiency pass to higher concentration of drug (solution of 0,1%).
Features of use:
Drug should not be used continuously throughout the long periods (more than 10 days in a row), at chronic rhinitises. Prolonged treatment by drug can cause converse effect.
It is not necessary to exceed the recommended drug doses, especially at treatment of children and elderly people.
It is necessary to appoint with care drug to patients with cardiovascular diseases, patients with an arterial hypertension, closed-angle glaucoma, a diabetes mellitus, with diseases of a thyroid gland, to patients who at use of adrenergic drugs have strong reactions which are shown in the form of sleeplessness, dizziness, a tremor, cardiac arrhythmia, increase in arterial pressure.
Due to the vasoconstrictive effect of drug increase in intraocular pressure is possible.
Use during pregnancy and feeding by a breast.
Drug cannot be used during pregnancy.
It is unknown whether xylomethazolinum with breast milk therefore women who nurse children can use drug only if according to the doctor is allocated, the expected advantage for mother exceeds potential risk for the child.
Ability to influence speed of response at control of motor transport or work with other mechanisms.
Drug does not influence ability to manage vehicles and difficult mechanisms at use in the recommended doses.
Children. It is not recommended to use drug the newborn up to 3 months.
For treatment of newborns 3 months are more senior and children till 1 year use drug only on doctor's orders.
ÖáÓ¼áº«½¿¡® 0,05% solution is shown to children up to 6 years.
ÖáÓ¼áº«½¿¡® 0,1% solution is shown to children 6 years are more senior.
By-effects in the form of burning, prickings, dryness in a nose, sneezing, nausea, an asthma, a Quincke's disease are possible. In isolated cases system allergic reactions are possible. At long use or frequent use of high concentration manifestations of resorptive effect in the form of dizziness, a headache, sleeplessnesses, vomitings, increases in arterial pressure, heartbeat, disturbance of a cordial rhythm, a short-term vision disorder can be noted a rhinedema. At especially long use of drug in high doses the depression can develop.
Interaction with other medicines:
Фармазолин® interacts with other medicines only with resorptive effect. Preparaty-adrenomimetiki other groups strengthen action of Pharmazolina®. Adrenolytic drugs and sympatholytics, antagonists of calcium weaken its effect. Drug strengthens hypertensive effect of tricyclic antidepressants and monoamine oxidase inhibitors on cardiovascular system.
Hypersensitivity to any component of drug, pregnancy, a transfenoidalny hypophysectomy or existence in the anamnesis of transnasal/transoral surgical interventions with an exposure of a firm meninx.
At too frequent instillation or use of drug in the increased concentration overdose symptoms in the form of a headache, dryness in a nose, nausea, depressions, increases in arterial pressure, a short-term vision disorder can be shown. It is necessary to stop use of drug and to apply drugs antagonists: sympatholytics and α-adrenoblockers ((((((((((phentolamine, Tropaphenum), symptomatic therapy. If drug was accidentally drunk, it is necessary to wash out a stomach, to accept purgatives and enterosorbents, to carry out treatment by α-adrenoblockers, symptomatic therapy.
Period of validity 3 years. After opening of a bottle drug is good for use of 28 days. To store drug in original packaging, the place protected from light at a temperature from 15 to 25 °C. Not to use drug after the termination of the period of validity specified on packaging. To store in the place, unavailable to children.
On 10 ml in a bottle or in a bottle with opening control, enclosed in a pack.