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Galavit

Препарат Галавит. ЗАО "ЦСМ Медикор" Россия



General characteristics. Structure:

Active agent: аминодигидрофталазиндион sodium of 25 mg

Excipients: sorbitol, starch, lactose, calcium stearate, talc, рацементол (menthol).




Pharmacological properties:

Immunomodulatory drug with antiinflammatory action.

The mechanism of action is connected with ability to influence functional and metabolic activity of macrophages. At inflammatory diseases reversibly (on 6-8 h) inhibits excess synthesis of a factor of a necrosis of tumors, interleykina-1 and other pro-inflammatory cytokines, active forms of oxygen the hyper elicited macrophages defining extent of inflammatory reactions, their recurrence, and also expressiveness of intoxication. Normalization of a functional condition of macrophages leads to recovery of the antigen presenting and regulating function of macrophages, decrease in level of an autoaggression.
Drug stimulates bactericidal activity of neutrocytes, strengthening phagocytosis and increasing nonspecific resistance of an organism to infectious diseases.
The main pharmacological effects are observed during 72 h.

Pharmacokinetics. It is brought out of an organism, generally by kidneys. At hypoglossal use of T1/2 makes 30 min.


Indications to use:

As an immunomodulator and anti-inflammatory drug in complex therapy of immunodeficiency at adults and teenagers 12 years are more senior:
— the infectious intestinal diseases which are followed by intoxication and/or diarrhea;
peptic ulcer of a stomach and duodenum;
— viral hepatitis;
— the chronic recurrent diseases caused by a herpes virus;
— the diseases caused by the virus of papilloma of the person (VPP);
— infectious and inflammatory diseases of an urogenital path (urethritis of a Chlamidia and mecotic etiology, Chlamidia prostatitis, acute and chronic salpingo-oophoritis, chronic endometritis);
— pyoinflammatory diseases of bodies of a small pelvis (VZOMT);
— postoperative rehabilitation of patients with a hysteromyoma;
— complications of the postoperative period at patients of reproductive age;
— purulent surgical diseases (burn defeats, chronic osteomyelitis, gangrenous appendicitis with an omentitis, peritonitis, purulent pleurisy);
— postoperative it is purulent - septic complications and their prevention (including at oncological patients);
— chronic recurrent furunculosis, erysipelatous inflammation;
— asthenic states, neurotic and somatoformny frustration, decrease in physical effeciency (including at athletes);
— mental, behavioural and post-abstinent disorders at alcohol and drug addiction;
— inflammatory diseases of a mucous membrane of an oral cavity and throat, disease of a parodont;
— frequent recurrent respiratory diseases and ENT organs of a bacterial and virus etiology (including frequent SARS, bronchitis, pneumonia, adenoid disease, chronic otitis, chronic adenoiditis) and their prevention.


Route of administration and doses:

Podjyazychno: according to 1 tab. daily to 4 times a day or according to 2 tab. daily to 2 times a day, depending on the diagnosis and disease severity.

At frequent recurrent respiratory diseases and ENT organs of a bacterial and virus etiology (frequent SARS, bronchitis, pneumonia, adenoid disease, chronic otitis, chronic adenoiditis): to apply 4 times a day according to 1 tab. within 5 days, then 1 tab. 4 times every other day a course up to 15 days.

For prevention of acute respiratory infections and flu: according to 1 tab. 2 times a day a course of 5-10 days.

At the acute infectious intestinal diseases which are followed by a diarrheal syndrome: an initial dose — 2 tab. once, then according to 1 tab. 3-4 of time a day before stopping of symptoms of intoxication within 3–5 days.

At a peptic ulcer of a stomach and duodenum: in the acute period — the first 2 days — according to 1 tab. 4 times a day, then in each 3 days according to 1 tab. 4 times a day, a course — 2–3 weeks. In the chronic period — 5 days according to 1 tab. 4 times a day, then in each 3 days according to 1 tab. 4 times a day a course to 3 weeks.

At a viral hepatitis of various etiology: in the acute period of a disease an initial dose — according to 2 tab. 2 times a day before stopping of symptoms of intoxication and an inflammation. The subsequent continuation of a course according to 1 tab. 4 times a day in each 3 days a course to 2-3 weeks is possible.

At the chronic recurrent diseases caused by a herpes virus — according to 1 tab. 4 times a day within 10 days. Then according to 1 tab. 4 times a day in a day within 10 days.

At the diseases caused by a virus of papilloma of the person: 5 days according to 1 tab. 4 times a day, then according to 1 tab. 4 times a day every other day a course to 2-3 weeks.

At urogenital diseases (an urethritis of a Chlamidia and mecotic etiology, Chlamidia prostatitis): in the first day — 2 times according to 2 tab., then according to 1 tab. 4 times a day every other day a course to 2 weeks (depending on weight of pathological process).

At a salpingo-oophoritis, an endometritis: during the acute period — 2 days according to 2 tab. 2 times a day, then according to 1 tab. 4 times a day in each 3 days during 3 weeks. In the chronic period — 5 days according to 1 tab. 4 times a day, then according to 1 tab. 4 times a day in each 3 days a course to 2-3 weeks.

At acute and chronic purulent diseases of bodies of a small pelvis: in the acute period in the first day — according to 2 tab. 2 times a day, then 3 days according to 1 tab. 4 times a day, then according to 1 tab. 4 times a day every other day within 10 days. In the chronic period — 5 days according to 1 tab. 4 times a day, then according to 3–4 tab. in each 3 days a course to 3 weeks.

For postoperative rehabilitation of patients with a hysteromyoma and at complications of the postoperative period at women of reproductive age: 5 days according to 1 tab. 4 times a day, then according to 1 tab. 4 times a day every other day a course to 2 weeks.

At purulent surgical diseases (burn defeats, chronic osteomyelitis, gangrenous appendicitis with an omentitis, peritonitis, purulent pleurisy): to apply 4 times a day according to 1 tab. within 5 days, then 1 tab. 4 times every other day a course up to 15 days.

For prevention and treatment of surgical complications in to - and the postoperative period (including at oncological patients): according to 1 tab. 4 times a day within 5 days before operation, within 10 days after transaction of 1 tab. 4 times every other day and during 3 weeks according to 1 tab. 4 times in 3 days. At a severe disease in the first day according to 2 tab. 2 times a day.

At a chronic recurrent furunculosis, an ugly face: 5 days according to 1 tab. 4 times a day, then according to 1 tab. 4 times every other day a course to 3 weeks.

At asthenic states, neurotic and somatoformny frustration, at mental, behavioural and post-abstinent disorders, at patients with alcohol and drug addiction: 5 days according to 1 tab. 4 times a day, then according to 1 tab. 4 times in each 3 days during 3 weeks. For increase in physical effeciency: according to 1 tab. 4 times every other day within 10 days, then according to 1 tab. 4 times a day in 3 days a course to 3 weeks.

At inflammatory diseases of a mucous membrane of an oral cavity and throat, diseases of a parodont: an initial dose — 1 tab. 4 times a day within 5 days, then according to 1 tab. 4 times a day in 3 days a course to 3 weeks.


Features of use:

At simultaneous use with the drug Galavit® decrease in course doses of antibiotics is possible.


Side effects:

Seldom: allergic reactions.


Interaction with other medicines:

Cases of incompatibility with other medicines are noted.


Contraindications:

— pregnancy;
— lactation;
— individual intolerance.

Use of the drug GALAVIT® at pregnancy and feeding by a breast
Drug is contraindicated at pregnancy and in the period of a lactation.


Overdose:

So far about cases of overdose of the drug Galavit® it was not reported.


Storage conditions:

Drug should be stored in protected from light, the place, unavailable to children, at a temperature not above 25 °C.


Issue conditions:

Without recipe


Packaging:

Tablets hypoglossal 25 mg: 10 pieces.



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