DE   EN   ES   FR   IT   PT


medicalmeds.eu Medicines Remedy for a benign hyperplasia of a prostate of a plant origin. Простамол® Uno

Простамол® Uno

Препарат Простамол® Уно. Berlin-Chemie AG/ Menarini Group (Берлин-Хеми АГ/ Менарини Групп) Германия


Producer: Berlin-Chemie AG/Menarini Group (Berlin-Hemi AG/Menarini Group) Germany

Code of automatic telephone exchange: G04CX02

Release form: Firm dosage forms. Capsules.

Indications to use: Chronic prostatitis. Pain syndrome. Benign hyperplasia of a prostate. Dysuria.


General characteristics. Structure:

Active ingredient: Spirit extract of fruits of a palm tree creeping (9-11:1) - 320 mg

Excipients:

Capsule cover: gelatin suktsinilirovanny, глицерол, the water purified titanium dioxide, dye ferrous oxide black, dye crimson [Ponso 4R].




Pharmacological properties:

Extract of fruits of a palm tree of creeping (Serenoa repens) renders anti-proliferative, anti-androgenic, antiinflammatory and antiedematous effects which are selectively shown at the level of a prostate. At the same time drug does not exert impact on the level of sex hormones in a blood plasma, does not influence a potentiality and a libido and does not change the level of prostatospetsifichesky antigen in a blood plasma.

Local anti-proliferative effect of drug is shown by decrease of the activity of growth factors (first of all epidermal and fibroblastichesky), braking of linkng of receptors of prolactin with the subsequent disturbance of processes of signal transmission in cells of a prostate and acceleration of processes of apoptosis of cells of a prostate that is reflected in growth inhibition of volume of a prostate.

The mechanism of local anti-androgenic action is caused by inhibition of synthesis of dihydrotestosterone from testosterone (due to enzyme 5 oppression - alpha reductase I and II of types) and its fixings to cytosolic receptors of cells of a prostate that interferes with penetration of hormone into a kernel. As a result of it protein synthesis decreases.

The mechanism of local antiinflammatory action is caused by the fact that extract of fruits of a palm tree of creeping (Serenoa repens) inhibits activity of a phospholipase of A2, 5 - of a lipoxygenase and release of arachidonic acid, thereby reduces synthesis of prostaglandins and leukotrienes which are inflammation mediators. Простамол® Uno reduces permeability of capillaries and vascular стаз, reduces puffiness and inflammatory process in a prostate, eliminates a compression of a neck of a bladder and the urinary channel, improving indicators of urodynamic.

Thus, the drug Prostamol® of Uno promotes, on the one hand, reduction of expressiveness of pathological symptoms of a benign hyperplasia of a prostate (a dysuria, a pollakiuria, a nocturia, painful feelings and feeling of tension at an urination, incomplete bladder emptying), to increase in volume and force of an urination. On the other hand, against the background of use of drug the further growth and increase in volume of a prostate is slowed down.

Pharmacokinetics. Extract of fruits of a palm tree of creeping (Serenoa repens) is quickly soaked up. After oral administration the maximum concentration in plasma is reached after about 1,5 hours.


Indications to use:

Benign hyperplasia of a prostate (I and II stage).
• Elimination of dysuric symptoms (frustration of an urination, a night pollakiuria, a pain syndrome, etc.) at chronic prostatitis.


Route of administration and doses:

The drug Prostamol® of Uno is used on 1 capsule (320 mg) of 1 times a day at the same time, after food, without chewing, washing down with enough liquid. Duration of a course of treatment is not limited on time. The recommended therapy course duration - not less than three months.



Side effects:

Allergic reactions to drug components are possible. In rare instances - discomfort from digestive tract: nausea, heartburn (at reception on an empty stomach).


Interaction with other medicines:

Interaction with other medicinal substances is not revealed.


Contraindications:

Individual intolerance of components of drug.


Overdose:

Cases of overdose of the drug Prostamol® of Uno are not registered.


Storage conditions:

To store at a temperature not above 25 °C, in the place protected from light.

To store medicine in the place, unavailable to children!

Period of validity 3 years. Not to use after the period of validity specified on packaging.


Issue conditions:

Without recipe


Packaging:

Capsules on 320 mg.

On 15 capsules in the blister (aluminum PVC/PVDH/foil).

On 1, 2 or 4 blisters together with the application instruction in a cardboard pack.



  • Сайт детского здоровья