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Dibazolum

Препарат Дибазол . ОАО "Биохимик" Республика Мордовия


Producer: JSC Biokhimik Republic of Mordovia

Code of automatic telephone exchange: C04AX

Release form: Liquid dosage forms. Solution for injections.

Indications to use: Peptic ulcer of a stomach. Pylorospasm. Hypertensive crisis.


General characteristics. Structure:

Active ingredient: 10 g of Bendazolum of a hydrochloride (Dibazolum).

Excipients: ethanol (alcohol) of 95%, глицерол (glycerin); 0,1 M Acidum hydrochloricum solution, water for injections.




Pharmacological properties:

Pharmacodynamics. The antispasmodic of myotropic action, renders a spasmolytic deyyostviye on all smooth muscle bodies, expands vessels. Lowers an arterial davyoleniye due to reduction of cordial emission and expansion of peripheral vessels. Hypotensive activity very moderate, and the effect is short.

Pharmacokinetics. At intramuscular introduction anti-hypertensive action comes within 30-60 minutes, and at intravenous administration within 15-20 minutes. Action duration - 2-3 hours.


Indications to use:

Spasms of smooth muscles of internals (peptic ulcer of a stomach, spasms of the gatekeeper and intestines), hypertensive crisis.


Route of administration and doses:

Enter intravenously and intramusculary. At hypertensive crisis enter intravenously or intramusculary 30-40 mg (3-4 ml of 1% of solution). Along with Dibazolum it is possible to apply also other anti-hypertensive medicines.

At spasms of smooth muscles the drug is administered in a dose - 10-20 mg (1-2 ml of 1% of solution) intramusculary.


Features of use:

At prolonged use Dibazolum can weaken cordial activity and deterioration in indicators of the electrocardiogram is possible.

Pregnancy and period of feeding by a breast. As data on safety of drug for a fruit are absent, it cannot be applied during pregnancy. During feeding by a breast to apply only in that case when the advantage for mother, exceeds potential risk for the child.


Side effects:

At use of high doses there is a feeling of heat, the increased perspiration, a golovoyokruzheniye, nausea and a slight headache.

At a dose decline or drug withdrawal the called by-effects quickly pass. Allergic reactions are possible.


Interaction with other medicines:

Bendazolum (Dibazolum) warns caused a beta - adrenoblockers uvelicheyony the general peripheric vascular resistance.

At simultaneous use of Bendazolum and phentolamine hypotensive action of Bendazolum amplifies.

Bendazolum (Dibazolum) strengthens hypotensive action of anti-hypertensive and diuretiyochesky means.


Contraindications:

Hypersensitivity to drug. Drug is contraindicated at zaboleyovaniye which are followed by the raised muscle tone or a convulsive syndrome.



Storage conditions:

In the dry place at a temperature from 5 to 30 °C. In the place, unavailable to children, the Period of validity 4 years. Not to use after the expiry date specified on packaging


Issue conditions:

According to the recipe


Packaging:

Solution for intravenous and intramuscular administration of 10 mg/ml. 5 ml in ampoules of neutral glass. 5 ampoules in a blister strip packaging from a PVC film. 2 planimetric packagings place in a pack from a cardboard. 10 ampoules place in a pack from a cardboard with partitions or lattices, or a separator from a cardboard or paper bag. 10 ampoules place in a box from a cardboard. Put the application instruction and a knife in each pack or a box ampoule or the scarificator ampoule. When using ampoules with notches, rings of a break or points of a break the knife ampoule or the scarificator ampulyyony is not put.



Similar drugs

Dibazolum

Other peripheral vasodilators.



Препарат Дибазола. ОАО "Биохимик" Республика Мордовия

Dibazolum

Peripheral vazodilatator.



Препарат Дибазол . ОАО "Биохимик" Республика Мордовия

Dibazolum

Peripheral vazodilatator.





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