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medicalmeds.eu Medicines Probiotic. Пробифор®

Пробифор®

Препарат Пробифор®. ЗАО "Партнер" Россия



General characteristics. Structure:

Active ingredient: not less than 500 million colony-forming units (5х108, WHICH) the bifidobacteria occluded on absorbent carbon.

Excipients: lactoses monohydrate.




Pharmacological properties:

Pharmacodynamics. Anti-diarrheal effect of drug is caused by high concentration of the bifidobacteria (Bifidobacterium bifidum No. 1) occluded on particles of absorbent carbon, being antagonists of a wide range pathogenic (shigellas, salmonellas, golden staphylococcus, etc.) and conditionally pathogenic microorganisms (proteas, a klebsiyell, etc.).

Anti-infectious effect of drug is strengthened due to sorption of bifidobacteria on coal particles that leads to the accelerated normalization of a microbiocenosis of digestive tract, activation of recovery processes in mucous membranes and to increase in anti-infectious resistance of an organism.

Anti-toxic effect of drug is provided with bystry settling of intestines by microcolonies of bifidobacteria, recovery of normal microflora which interferes with penetration of toxins into internal environment of an organism and, being a natural biosorbent, accumulates the toxic substances getting from the outside or formed in an organism in a significant amount.

Bifidobacteria in high concentration activate pristenochny digestion of intestines, synthesis of vitamins and amino acids, strengthen protective function of intestines and a host defense of an organism.


Indications to use:

- diarrhea of various etiology;
- food toxicoinfections;
- acute intestinal infections of the bacterial and virus nature (the salmonelloses, shigelloses, coloenterites caused by pathogenic representatives of a sort of enterobakteriya or stafilokokka, a rotavirusny infection) or an unspecified etiology;
- the dysbacterioses of various etiology including which developed against the background of and after reception of antibiotics, cytostatic, radiation therapy; the complicating course of a viral hepatitis, cirrhosis, a divertuculosis of intestines of various localization;
- the newborn (including premature) to children with the burdened premorbidal background, since the period of stay in a maternity home, for improvement of a current of the period of adaptation, and also at the expressed dysbacterioses;
- to pregnant women by preparation for childbirth, Cesarean section and in the postoperative period.

Drug is used as a part of complex therapy:

- chronic infectious and nonspecific inflammatory diseases of a digestive tract (gastroduodenit, pancreatitis, a proctosigmoiditis, colitis, including ulcer colitis);
- patients with secondary immunodeficiency, at heavy infectious and inflammatory it is also purulent - septic diseases (sepsis, peritonitis, etc.); with skin diseases (atopic dermatitis, a streptoderma, eczema);
- syndrome of the angry intestines;
- acute respiratory viral infections and flu;
- surgical patients (including a traumatologic profile) for preoperative preparation and prevention of postoperative complications; at postgastrorezektsionny frustration and states after cholecystectomias;
- oncological patients when carrying out chemotherapy, radiation therapy, before and after surgical interventions.


Route of administration and doses:

At acute intestinal infection, food toxicoinfection, diarrhea:

  • to children up to 6 months on 1 package 2 times a day; to children 6 months on 1 package 3-4 times a day (possibly with a short interval at 2-3 o'clock), a course 2-3 days are more senior; at preservation of clinical symptoms the course of treatment is extended up to 4-5 days;
  • to children 7 years and the adult on 2-3 packages 2 times a day a course of 3-5 days are more senior;
  • the adult for the termination of diarrhea in early terms of a disease on 3 packages 2 times a day with an interval of 30 minutes – 1 hour; it is possible to increase amount of the accepted drug to 6 packages in one step by reception of 1 times a day, a course from 1 to 3 days.

At chronic pathology of digestive tract and functional intestinal disturbances – to children and adults once 3 packages during evening meal, the adult – are possible on 2 packages 2 times a day. Course of treatment of 5-15 days. At a severe disease children can increase amount of the accepted drug since 1 and the adult to 6 packages a day, and to increase a course up to 30 days.

At dysbacterioses of various etiology, persistent intestinal infections, at patients with immunodeficiency, with skin diseases, and also for improvement of a current of the period of adaptation at newborn children:

  • the premature newborn on 1 package 1-2 times a day;
  • to the full-term newborns and children up to 3 years on 1 package 2 times a day;
  • to children from 3 to 7 years – on 1 package 3 times a day;
  • to children 7 years and the adult on 2-3 packages – 2 times a day are more senior.

Course of treatment of 7-10 days.

In complex treatment of acute respiratory and viral infections and flu apply to patients of all age groups about 1-2 days of a disease on 1 package 3 times a day. Course of treatment 2 days.

To surgical patients, pregnant women by preparation for Cesarean section for the purpose of decrease in postoperative complications:

  • before operation on 1 package 3 times a day within 2-3 days; to the persons having the intestinal dysbiosis receiving antibiotics and himiopreparata, the preoperative course is extended up to 7 days;
  • from 2-7 in the afternoon after operation on 1 package 3 times a day within 2-3 days, according to indications – 7-10 days.

Пробифор® accept during meal, if necessary irrespective of meal. Drug before the use is mixed with liquid food, it is desirable fermented milk product, the newborn and to children of chest age – with maternal milk or mix for artificial feeding. It is possible to mix drug from 30-50 ml of boiled water of room temperature, at the same time the muddy suspension with parts of a sorbent of black color is formed. The received water suspension should be drunk, without trying to obtain full dissolution.


Features of use:

There are no precautionary measures.

Drug is allowed for use to women during the periods of pregnancy and breastfeeding. There are no special conditions of reception.

Drug does not influence ability to manage vehicles, mechanisms.


Side effects:

Are not established.


Interaction with other medicines:

At a concomitant use of Probifora® with vitamins (especially groups B) effect of drug amplifies. At reception of antibiotics the recommended interval between reception of an antibiotic and the drug Probifor® makes 3 – 4 hours.


Contraindications:

Inborn insufficiency of lactase. Glucose galactose absorption disturbance.


Overdose:

Cases of overdose were not observed.


Storage conditions:

Period of validity - 2 years. Not to use drug after a period of validity. Drug is not suitable for use after a period of validity, at outward change, at absence or indistinct marking on primary packaging, at disturbance of tightness of primary packaging. To store in the dry place at a temperature not above 10 °C. The lower bound of temperature is not limited. To store in the place, unavailable to children.


Issue conditions:

Without recipe


Packaging:

Powder in a package from multilayer metalpolymeric material. On 6, 10 or 30 packages of the application instruction in a pack from a cardboard.



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