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Pankreazim таб. No. 20, 50

Препарат Панкреазим таб. № 20, 50. ЗАО "Лекхим-Харьков" Украина


Producer: CJSC Lekhim-Kharkiv Ukraine

Code of automatic telephone exchange: A09A A02

Release form: Firm dosage forms. Tablets.

Indications to use: Abnormal liver function. Meteorism. Diarrhea.


General characteristics. Structure:

International and chemical name: pancreatin; structure: 1 tablet contains Pancreatinum - 0,240 g with the minimum fermental activity:
lipases - 8 000 ME FIP;
amylases - 5600 ME FIP;
proteases - 370 ME FIP;
excipients.




Pharmacological properties:

Fermental drug. The pancreatic enzymes (a lipase, amylase and protease) which are a part of drug facilitate digestion of fats, carbohydrates and proteins that promotes their full absorption in a small intestine. At pancreas diseases drug compensates insufficiency of its vneshnesekretorny function and promotes digestion process improvement. Tablets have a protective cover, insoluble in acid contents of a stomach which protects digestive enzymes from destruction under action рН a gastric juice.

Pharmacokinetics. Researches of pharmacokinetics of drug were not conducted.


Indications to use:

Insufficiency of vneshnesekretorny function of a pancreas (chronic pancreatitis, mucoviscidosis, etc.). The chronic inflammatory and dystrophic diseases of a stomach, intestines, liver, gall bladder, a state after a resection or radiation of these bodies which are followed by disturbances of digestion of food, a meteorism, diarrhea (as a part of a combination therapy). For improvement of digestion of food at patients with the GIT normal function in case of errors in food, and also at disturbances of chewing function, a forced long immobilization a slow-moving way of life. Preparation to radiological and to ultrasound examination of abdominal organs.


Route of administration and doses:

The dose is selected individually, depending on degree of insufficiency of function of a pancreas Usually drug is appointed in a dose of 1 - 4 tablet (that corresponds to 8 000 - 32 000 PIECES of FIP on a lipase) at each meal. Appoint tablets inside, before or during food, without chewing, washing down with a large amount of liquid, it is desirable not alkaline: water, fruit juice. The daily dose for adults makes 48 000 - 150 000 VD FIP (6 - 18 tablets). At full insufficiency externally - secretory function of a pancreas (for example, cystous fibrosis) the dose has to be increased about 400 000 PIECES of FIP a day that corresponds to daily need of the adult for a lipase.
The course of treatment can proceed of several days (at disturbance of process of digestion owing to errors in a diet) to several month and even years (in need of continuous replacement therapy).


Features of use:

At. a mucoviscidosis the dose of drug has to be adequate to amount of enzymes which is necessary for absorption of fats taking into account quality and amount of the consumed food.


Side effects:

At prolonged use hypersensitivity reactions are very seldom possible. At prolonged use of high doses of drug development of a hyper uricosuria is possible.


Interaction with other medicines:

Reduces iron absorption (especially at prolonged use).


Contraindications:

Acute pancreatitis, exacerbation of chronic pancreatitis, hypersensitivity to drug components.


Overdose:

Pankreazim does not contain the components causing poisonings. In case of developing of an allergy it is necessary to carry out usual antiallergenic measures (drug withdrawal, symptomatic therapy).


Storage conditions:

Drug should be stored in the dry, protected from light place at a temperature not above 15 °C.

Period of storage - 2 years.


Issue conditions:

According to the recipe



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