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Hydrocortisone of 1%

Препарат Гидрокортизон 1%. ОАО "Биохимик" Республика Мордовия


Producer: JSC Biokhimik Republic of Mordovia

Code of automatic telephone exchange: D07AA02

Release form: Soft dosage forms. Ointment.

Indications to use: Eczema. Allergic dermatitis. Contact dermatitis. Neurodermatitis. Psoriasis.


General characteristics. Structure:

Active ingredient: 1 g of Hydrocortisoni acetas.

Excipients: vaseline medical, lanolin anhydrous, pental, stearic acid, нипагин (methylparahydroxybenzoate), нипазол (пропилпарагидроксибензоат), the water purified.

Glucocorticosteroid ointment for topical administration.




Pharmacological properties:

Pharmacodynamics. The hydrocortisone is synthetic glucocorticoid drug for topical      administration. Has antiinflammatory, antiedematous, antipruritic effect.

Pharmacokinetics. After application collects in epidermis (generally in a granular layer). It is metabolized directly in epidermis, and further in a liver. It is allocated with kidneys and with bile


Indications to use:

The hydrocortisone ointment of 1% is applied at inflammatory and allergic diseases of skin of not microbic etiology: eczema, allergic and contact dermatitis, neurodermatitis, psoriasis.


Route of administration and doses:

Locally. Ointment is applied a thin layer on affected areas of skin by 2-3 times a day. Duration of a course of treatment depends on the nature of a disease and efficiency of therapy, making, as a rule, 6-14 days; at persistent disease it can be prolonged up to 20 days.

On the limited centers for strengthening of effect it is possible to use occlusive bandages.

At use of ointment for children of 2 years is also more senior it is necessary to limit the general duration of treatment and to exclude the actions leading to strengthening of a resorption of absorption of a steroid (warming, fixing and occlusive bandages)


Features of use:

Pregnancy and lactation. Glucocorticosteroids get through a placenta. Impact on a fruit can be especially expressed when putting drug on big surfaces.

It is recommended to observe extra care at use of drug in пе­риод pregnancies and lactations. Children In cases of use of drug for children, or under okklyuzionyony bandages duration of a course of treatment needs to be reduced by area of the person.

At children's age suppression of function of bark of adrenal glands can quicker razyovitsya. Besides, decrease in excretion of a growth hormone can be observed. At a drug primeyoneniya it is necessary to watch the body weight, growth, plasma cortisol level for a long time.

It is necessary to avoid hit of ointment in eyes. To children up to 12 years drug is naznayochat only under strict medical control. If after 7 days the primeneyoniya does not come improvements or the aggravation of symptoms, and also in case of resuming of symptoms in several days after cancellation of a preparayot is observed, use of drug it is necessary to stop and consult with vrayochy.

At prolonged treatment and/or drawing rekoyomendutsya to appoint a diet with restriction of sodium to big surfaces and raised soderzhaniyoy K+; to enter enough protein into an organism. It is necessary to control the ABP, the content of glucose in blood, a blood svertyvayeyomost, a diuresis, body weight of the patient, plasma cortisol level.


Side effects:

The phenomena of individual intolerance in the form of a hyperemia, puffiness and an itch in ointment sites of application can be observed.

At prolonged use also development of secondary infectious damages of skin, atrophic changes in it, a hypertrichosis is possible.

For the prevention of infectious damages of skin drug is recommended to appoint in combination with antibacterial and antifungal agents.

At prolonged use of ointment or use of an occlusive bandage, especially on big sites of defeat, development of a hypercorticoidism as manifestation of resorptive action of a hydrocortisone is possible.



Contraindications:

Use of drug is contraindicated at hypersensitivity to a hydrocortisone    or other components of drug, at wound, cankers, bacterial, viral and fungus diseases of skin, at a tuberculosis cutis and syphilitic damages of skin. The Rozatsea, vulgar eels, perioral dermatitis, skin tumors, children's age up to 2 years.

With care at a diabetes mellitus.

Drug do not appoint pregnant.


Overdose:

At prolonged use of drug in high doses perhaps poyavleyony hypercorticoidism symptoms.


Storage conditions:

In dry, protected from light and the place, unavailable to children. Period of validity 3 years. Not to use after the expiry date specified on packaging


Issue conditions:

Without recipe


Packaging:

Ointment for external use of 1%. 10 g place in tubas aluminum. Each tuba together with the application instruction is placed in a pack.



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