Sulfacylum-natrium

General characteristics. Structure:

Active ingredient: 200 mg of Sodium sulfacetamidum (Sulfacylum-natrium) in 1 ml of solution.

Excipients: Natrium thiosulfuricum, Acidum hydrochloricum of 1 M, water purified.

Pharmacological properties:

Pharmacodynamics. Antimicrobic bacteriostatic means, streptocide. The mechanism of action is caused by competitive antagonism with para-aminobenzoic acid, oppression of a digidropteroatsintetaza, disturbance of synthesis of the tetrahydrofolic acid necessary for synthesis of purines and pyrimidines.

It is active concerning gram-positive and gram-negative cocci, Escherichia coli, Shigella spp., Vibrio cholerae, Clostridium perfringens, Bacillus anthracis, Corynebacterium diphtheriae, Yersinia pestis, Chlamydia spp., Actinomyces israelii, Toxoplasma gondii.

Pharmacokinetics. Gets into fabrics and liquids of an eye. It is soaked up in a system blood stream through the inflamed conjunctiva.

Indications to use:

Conjunctivitis, blepharitis, purulent helcoma, prevention and treatment of a blennorea at newborns, gonorrheal and Chlamidia diseases of eyes at adults.

Route of administration and doses:

Dig in in a conjunctival sac 1-2 drops of 5-6 times a day. For prevention of a blennorea at newborns dig in on 1 drop of solution in each eye three times with an interval of 10 minutes.

Features of use:

The patients having hypersensitivity to furosemide, thiazide diuretics, sulphonylurea or inhibitors of a karboangidraza can have hypersensitivity to Sulfacetamidum natricum.

Side effects:

Burning, dacryagogue, gripes, itch in eyes, allergic reactions.

Interaction with other medicines:

Combined use with Procainum and pantocain reduces bacteriostatic effect. It is incompatible with silver salts.

Contraindications:

Individual sensitivity to drug components.

Storage conditions:

In the place protected from light, at a temperature not above 15 °C. To store in the places unavailable to children. A period of validity - 2 years. A drug period of validity after opening - 7 days (for drug in a tube droppers). A drug period of validity after opening - 1 month (for drug in a bottle droppers). Not to use after the expiry date specified on packaging.

Issue conditions:

According to the recipe

Packaging:

Drops eye 20%. Packaging: 1,5 ml, 2 ml or 5 ml in a tube dropper polymeric. 1, 2, 4, 5 or 10 tube droppers with the application instruction of drug in a pack from a cardboard with partitions or without partitions. 5 ml or 10 ml in a bottle dropper polymeric. The 1 or 2 bottle dropper with the application instruction of drug in a pack from a cardboard.