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medicalmeds.eu Medicines Corticosteroids in a combination with antimicrobic drugs. Гентадекс

Гентадекс

Препарат Гентадекс. РУП "Белмедпрепараты" Республика Беларусь


Producer: RUP of Belmedpreparata Republic of Belarus

Code of automatic telephone exchange: S01CA01

Release form: Liquid dosage forms. Drops are eye.

Indications to use: Blepharitis. Conjunctivitis. Keratitis. Iridocyclitis. Sclerite. Episcleritis. Eczema century. The infected eczema.


General characteristics. Structure:

Active ingredients: 1 mg of dexamethasone of sodium phosphate, 3 mg Gentamycini sulfas (in terms of gentamycin basis).




Pharmacological properties:

Pharmacodynamics. The combined drug for topical administration in ophthalmology which action is caused by the components which are its part: sodium dexamethasone glucocorticosteroid phosphate and antibiotic of group of aminoglycosides Gentamycini sulfas.

Has antibacterial, antiinflammatory, antiallergic effect. Reduces pain, burning, dacryagogue, a photophobia.


Indications to use:

The bacterial diseases of a front piece of an eye caused by microorganisms, sensitive to gentamycin:
- blepharites;
- conjunctivitis;
- a keratitis (without damage of an epithelium);
- iridocyclites;
- sclerites, episclerites;
- the infected skin eczema a century.

Allergic processes of front department of an eye, at accession by a bacterial infection. Prevention and treatment of the inflammatory phenomena in the postoperative period.


Route of administration and doses:

At the easy course of infectious process dig in 1-2 drops of drug in a conjunctival sac of an eye each 4 hours. In case of development of heavy infectious process drug is dug in each hour. In process of reduction of the inflammatory phenomena the frequency of instillations of drug decreases. Duration of use of drug should not exceed 7 days, except cases of explicit positive dynamics of a disease (dexamethasone can mask it is hidden the proceeding infections, and long use of gentamycin can promote development of steady flora).


Features of use:

Pregnancy and lactation: use of drug at pregnancy and feeding by a breast within 7-10 days is allowed (no more) if the importance of effect exceeds risk of development of side effects for mother and a fruit.

Before use of drug it is necessary to remove soft contact lenses and again to establish them not earlier than in 15 minutes.

Influence on ability to drive the car and potentially dangerous mechanisms: it is not recommended to use drug just before control of vehicles or work with mechanisms as dacryagogue after a drug instillation is possible.

At an instillation it is not necessary to touch with a pipette tip an eye.


Side effects:

Allergic reactions: irritation, burning, pain, itch, dermatitis.

At prolonged use of medicine increase in intraocular pressure with development of a symptom complex of glaucoma (at use of eye drops of Gentadeks within more than 7 days it is regularly necessary to measure intraocular pressure) is possible; development of a zadnekapsulyarny cataract; thinning and perforation of a cornea; accession of a consecutive (fungal) infection.

Directly after an instillation perhaps short-term burning sensation, dacryagogue, a conjunctiva hyperemia.


Interaction with other medicines:

Gentamycini sulfas which is a part of medicine is an antibiotic from group of aminoglycosides to which it is inherent nefro-and ototoxicity, especially in case of use in high doses and at patients with a renal or liver failure.

It is not necessary to use drug together with other antibiotics having ototoksichesky and nephrotoxic effect (streptomycin, Monomycinum, Kanamycinum, фрамецитин).

At prolonged use with yodoksuridiny strengthening of destructive processes in a cornea epithelium is possible.


Contraindications:

The increased individual sensitivity to any of medicine components; virus (including herpetic) or fungal infections, tuberculosis, purulent inflammation of eyes, trachoma; disturbance of integrity of an epithelium of a cornea and thinning of a sclera.


Overdose:

At local use of eye drops гентадекс the probability of overdose of drug is extremely small. At the same time, prolonged use of drug can have systemic action.

Symptoms: at overdose at topical administration of eye drops гентадекс aggravation of side effect of components of drug is possible.

Treatment: drug it is necessary to cancel and see a doctor. There is no specific antidote.



Issue conditions:

According to the recipe


Packaging:

Solution (drops eye) (1 mg +3mg) / 1 ml in a tube droppers on 1 ml No. 2; in bottles on 5 ml.



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