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medicalmeds.eu Medicines Means for use in ophthalmology. Antiallergic means. Лекролин®

Лекролин®

Препарат Лекролин®. OY Santen(АО Сантэн) Финляндия


Producer: OY Santen (JSC Sangteng) Finland

Code of automatic telephone exchange: S01GX01

Release form: Liquid dosage forms. Drops are eye.

Indications to use: Allergic conjunctivitis. Keratitis. Keratoconjunctivitis.


General characteristics. Structure:

Active ingredient: 20 mg of a kromoglikat of sodium.

Excipients: a benzalkoniya chloride, dinatrium эдетат, глицерол, polyvinyl alcohol, water for and.

Eye drops.




Pharmacological properties:

Pharmacodynamics. Antiallergic drug, stabilizer of membranes of mast cells. Interferes with degranulation of mast cells and allocation from them of a histamine, bradikinin, leukotrienes (including slowly reacting substance) and other biologically active agents.

Drug is most effective at preventive use.

The full clinical effect at allergic diseases of eyes is reached in several days or weeks of treatment by drug.

Pharmacokinetics. Absorption. At use of eye drops absorption of a kromoglikat of sodium through a mucous membrane of an eye is insignificant.

System bioavailability makes less than 0.1%.

Removal. T1/2 makes 5-10 min.


Indications to use:

allergic conjunctivitis;

— allergic keratitis;

keratoconjunctivitis;

— the irritation of a mucous membrane of eyes caused by allergic reactions (environment factors, professional harm, means of household chemicals, cosmetics, ophthalmologic drugs, pollen of plants and dandruff of domestic animals).


Route of administration and doses:

Drug is appointed on 1-2 drops in each conjunctival sac of 4 times/days.

At seasonal allergic conjunctivitis treatment should be begun right after emergence of the first symptoms or to apply preventively prior to the beginning of a season of emergence of pollen. Treatment is continued during the whole season of blossoming or longer if symptoms remain.

Rules of use of the drug Lekrolin® in a tube dropper

1. To open a package along a dashed line.

2. To separate one tube dropper.

3. To carefully close a package.

4. To be convinced that solution is in the lower part a tube dropper and to open a tube dropper.

5. To dig 1-2 drops in eyes.

The dose which is contained in a tube dropper is sufficient for one instillation in both eyes. After a tube dropper disposable it is necessary to throw out even if there were contents.


Features of use:

At pregnancy and in the period of a lactation (breastfeeding) drug should be used with care and only in that case when the estimated advantage for mother surpasses potential risk for a fruit or the baby.

Use for children. Contraindication: children's age up to 4 years.

The eye drops of Lekrolin® packed into a bottle dropper contain preservative a benzalkoniya chloride which can cause symptoms of irritation of eyes. Therefore the patients carrying contact lenses should remove them before use of drops and to establish back not earlier than in 15 min. after an instillation.

The eye drops of Lekrolin® packed into a tube dropper are intended for single application, do not contain preservative therefore do not slow down healing of conjunctival or corneal wounds. These drops can be applied at patients with hypersensitivity to preservatives, and also at the patients using contact lenses of any type.

It is not necessary to touch eyes a pipette tip.

The bottle needs to be closed after each use.

Influence on ability to driving of motor transport and to control of mechanisms. Patients who after instillation of drug have a short-term disturbance of clearness of visual perception should not drive the car or to work with the equipment, machines or any other equipment demanding the clearness of visual perception right after use of eye drops.


Side effects:

From an organ of sight:> 1/100 - a short-term burning sensation, local irritation of eyes and quickly taking place disturbance of clearness of visual perception.

Others: <1/10 000 - allergic reactions.


Interaction with other medicines:

Negative symptoms of interaction of kromoglitsiyevy acid with other medicines are noted.

At use of kromoglitsiyevy acid reduction of need for use of the ophthalmologic drugs containing GKS is possible.


Contraindications:

— children's age up to 4 years;

— hypersensitivity to drug components.


Overdose:

At topical administration of drug the overdose is improbable. In pilot studies it is shown that local and system toxicity of kromoglitsiyevy acid is very small.

Symptoms: nausea is possible.

Treatment: performing symptomatic therapy.


Storage conditions:

Drug should be stored in the unavailable to children, protected from light place at a temperature from 15 °C to 25 °C. Period of validity 3 years. After opening of a bottle dropper or opening of a package about a tube droppers a period of validity of 1 month.


Issue conditions:

According to the recipe


Packaging:

0.25 ml - a tube dropper (10) - packages paper laminated three-layered (2) - packs cardboard.

10 ml - a bottle dropper plastic (1) - packs cardboard.



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