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medicalmeds.eu Medicines Koronarodilatiruyushchy means of a reflex effect. Validol with glucose

Validol with glucose

Препарат Валидол с глюкозой. ОАО "Ирбитский химико-фармацевтический завод" Россия


Producer: JSC Irbit Chemical and Pharmaceutical Plant Russia

Code of automatic telephone exchange: C01EX

Release form: Firm dosage forms. Tablets are hypoglossal.

Indications to use: Cardialgia. Neurosis. Sea sickness. Aeroembolism.


General characteristics. Structure:

Active agents: left menthol solution in mentit isovalerate (Validol) – 60 mg; Monohydrate Dextrosums (monohydrate glucose) – 188 mg.

Excipients:  sugar (sucrose), aerosil (silicon dioxide colloid), stearic acid – enough before receiving a tablet weighing 800 mg.

Description. Tablets of a ploskotsilindrichesky form, color, white or white with grayish impregnations, with risky and a facet, with a characteristic smell of menthol.




Pharmacological properties:

Pharmacodynamics. Has sedative effect, possesses the moderate reflex vasodilating effect caused by irritation of sensitive nerve terminations. Stimulates development and release of enkephalins, endorphines and some other peptides, kinin (at the expense of irritation of receptors of a mucous membrane) which take active part in regulation of permeability of vessels, formation of pain. At sublingual reception the therapeutic effect, on average, occurs in 5 min., at the same time to 70% of drug is released within 3 min.

Dextrosums monohydrate (glucose monohydrate) participates  in various processes of a metabolism in an organism, participates in metabolic processes.

Pharmacokinetics. At sublingual use it is absorbed from a mucous membrane of an oral cavity. After absorption it biotransformirutsya in a liver and  it is removed by kidneys in the form of glucuronides.

Dextrosums monohydrate is completely acquired by an organism, is not removed by kidneys (emergence in urine is a pathological sign).


Indications to use:

Functional cardialgias, neurosises and also as antiemetic at sea and aeroembolism.


Route of administration and doses:

Validol is appointed the adult under language. The tablet should be kept in a mouth under language to a full rassasyvaniye. Accept on 1 tablet 2-3 times a day. 

Daily frequency rate and duration of reception is defined depending on efficiency of treatment. At insufficiently expressed effect or when at certain patients the next 5 min. after administration of drug the effect is not observed, it is necessary to see a doctor for an exception of heart attack or purpose of other therapy. At the severe and strengthening pains, especially against the background of the previous heart diseases (an angina of exertion, the postponed myocardial infarction and others) it is necessary to call the Ambulance.


Features of use:

1 tablet contains 188 mg of a dextrose of monohydrate (monohydrate glucose), 450 mg of sugar (sucrose) that corresponds 0,054 XE that should be considered a sick diabetes mellitus.


Side effects:

At long reception slight nausea, dacryagogue, dizziness can be observed.

These phenomena usually pass independently.


Interaction with other medicines:

At combined use with neurotropic means oppressing like action strengthens the oppressing action of the last on the central nervous system.

Simultaneous use of Validol with glucose with nitrates reduces a headache which arises at their use.


Contraindications:

Hypersensitivity to drug components. 

Children's age up to 3 years.

With care: to appoint a sick diabetes mellitus (drug contain sugar).


Overdose:

Symptoms: headache, nausea, excitement, disturbance of action of the heart, falling of arterial pressure, oppression of the central nervous system.

Treatment: to cancel drug. Symptomatic therapy.


Storage conditions:

In the dry place, at a temperature from 12 to 18 °C. To store in the place, unavailable to children.


Issue conditions:

Without recipe


Packaging:

Tablets are hypoglossal.

10 tablets in a blister strip packaging. 

1000 blister strip packagings with  the equal number of application instructions place in a box from a cardboard.



Similar drugs

Validol

The combined drugs for treatment of heart diseases. Vazodilatatora.



Validol

Koronarodilatiruyushchy means of a reflex effect.





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