DE   EN   ES   FR   IT   PT


medicalmeds.eu Medicines Glucocorticoids in combinations. Kandibiotik

Kandibiotik

Препарат Кандибиотик. Glenmark Pharmaceuticals Ltd.(Гленмарк Фармасьютикалз Лтд) Индия


Producer: Glenmark Pharmaceuticals Ltd. (Glenmark Pharmasyyutikalz Ltd) India

Code of automatic telephone exchange: S02CA

Release form: Liquid dosage forms. Drops are ear.

Indications to use: Outside otitis. Acute otitis. Chronic otitis.


General characteristics. Structure:

Active agents: chloramphenicol – 50 mg, beclomethasone Dipropionas (anhydrous) – 0,25 mg, Clotrimazolum – 10 mg, hydrochloride lidocaine monohydrate, in terms of lidocaine a hydrochloride – 20 mg;

Excipients: глицерол, propylene glycol.




Pharmacological properties:

Antimicrobic local, antibacterial, antiinflammatory local, locally anesthetic.
Clotrimazolum (derivative an imidazole) - antifungal broad-spectrum agent for topical administration.
The antifungal effect of Clotrimazolum is connected with disturbance of synthesis of the ergosterol which is a part of a cellular membrane of mushrooms that changes permeability of a membrane and causes the subsequent lysis of a cell. Chloramphenicol - a bacteriostatic antibiotic of a broad spectrum of activity. Breaks process of synthesis of protein in a microbic cell. It is active concerning gram-positive and gram-negative bacteria.
Beclomethasone Dipropionas - a glucocorticosteroid. Has antiinflammatory and antiallergenic effect. Lidocaine - mestnoanesteziruyushchy means. Causes reversible blockade of carrying out an impulse on nerve fibrils due to blocking of passing of ions of sodium through a membrane.

Pharmacokinetics. Researches of pharmacokinetics of drug were not conducted.


Indications to use:

Allergic and inflammatory diseases of an ear, including:
- acute diffusion outside otitis;
- acute otitis of a middle ear;
- chronic otitis in an aggravation stage;
- a state after surgical interventions on an ear.


Route of administration and doses:

Locally. Dig in in outside acoustical pass 4-5 drops 3-4 times a day. Improvement of a state occurs within 3-5 days. The course of treatment makes 7-10 days.


Features of use:

There are no data.


Side effects:

The itch, burning in a drug site of application is in rare instances observed. Allergic reactions are possible.


Interaction with other medicines:

It was not studied.


Contraindications:

Hypersensitivity to drug components.
Children's age (up to 6 years).
Disturbance of integrity of a tympanic membrane.

Pregnancy and lactation
The issue of expediency of purpose of drug during pregnancy has to be resolved individually after consultation of the doctor. Purpose of drug is possible if the estimated advantage for mother exceeds potential risk for a fruit.


Overdose:

There are no data.


Storage conditions:

To store in the dry, protected from light place at a temperature not above 25 °C. To store in the place, unavailable to children.


Issue conditions:

According to the recipe


Packaging:

Drops are ear. On 5 ml in the bottle from dark glass which is closed the screw-on aluminum cap with control of the first opening. The pipette inserted into a plastic screw cap is applied to a bottle. Each bottle complete with the pipette placed in the soldered polyethylene bag, and the application instruction is placed in a cardboard pack.



  • Сайт детского здоровья