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medicalmeds.eu Medicines Antiallergic means — H1-histamine of receptors a blocker. Alerza

Alerza

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Producer: Ipca Laboratories (Ipk Laboratoriya) India

Code of automatic telephone exchange: R06AE07

Release form: Firm dosage forms. Tablets.

Indications to use: Allergic rhinitis (cold). Allergic conjunctivitis. Seasonal conjunctivitis. Pollinosis. Chronic idiopathic small tortoiseshell. Dermatosis. Skin itch. Skin rash.


General characteristics. Structure:

Active agent: tsetirizina hydrochloride of 10 mg.




Pharmacological properties:

Active agent of drug - цетиризин, concerns to group of competitive antagonists of a histamine, blocks H1 - histamine receptors. Tsetirizin exerts impact on a gistaminzavisimy stage of allergic reactions, and also reduces migration of eosinophils, limits release of mediators of an inflammation at a cellular stage of allergic reaction. Prevents development and facilitates the course of allergic reactions, has antiexudative, antipruritic effect, has practically no anticholinergic and antiserotoninovy effect. In therapeutic doses has practically no sedative effect.

Pharmacokinetics. It is quickly soaked up at intake. Cmax in serum is reached in 1 h after oral administration. In small amounts it is metabolized in a liver. T1/2 makes at adult 7-10 h, children have 6-12 years - 6 h.


Indications to use:

— seasonal and year-round allergic rhinitis and conjunctivitis;
pollinosis (hay fever);
— the idiopathic small tortoiseshell and other allergic dermatosis which are followed by an itch and rashes.


Route of administration and doses:

Inside to adults and children 12 years of-1 tablet (10 mg) of 1 times/days are more senior.
To children of 6-12 years - on 1 tablets (10 mg) - 1 time/days or on 1/2 tablets (5 mg) of 2 times/days.
To patients with a renal failure of moderate severity (KK of 11-13 ml/min.), to the patients who are on a hemodialysis (KK less than 7 ml/min.) and to patients with disturbance of hepatic function recommends to appoint on 1/2 tablets/days.

At the accidental admission of time of administration of drug, the next dose should be accepted at the first opportunity. If time of the next administration of drug comes, the next dose should be accepted according to the schedule, without increasing the general dose.

Alerz's drug can be accepted regardless of meal.
Tablets should be swallowed, without chewing, washing down with a small amount of water.


Features of use:

The persons accepting drug need to be careful during the work demanding the high speed of mental and physical reactions (control of vehicles, service of cars, work at height, etc.).


Side effects:

The headache, drowsiness, dizziness, excitement, dryness in a mouth, disturbances are in some cases possible from a GIT in the form of dyspepsia, an abdominal pain, a meteorism.
Allergic reactions: Quincke's disease, rash, small tortoiseshell, itch.


Interaction with other medicines:

It is not recommended to combine without consultation of the doctor administration of drug of Alerz with other medicines.

At a concomitant use with the broncholitic means containing theophylline in quality of active ingredient increase in frequency of side effects of a tsetirizin is possible.

Data on interaction of a tsetirizin with alcohol are not obtained so far, despite it, the use of alcoholic drinks at treatment tsetiriziny is not recommended.


Contraindications:

— children's age (up to 6 years);
— pregnancy, lactation period;
— hypersensitivity to Hydroxyzinum and other components of drug.

With care at an abnormal liver function and/or kidneys, to elderly people.

Use of drug ALERZA at pregnancy and feeding by a breast
Contraindicated: pregnancy, lactation period.

Use at abnormal liver functions
With care at an abnormal liver function.

Use at renal failures
With care at a renal failure.

Use for elderly patients
With care to elderly people.

Use for children
Contraindication: children's age (up to 6 years).


Overdose:

Symptoms: administration of drug once in a dose over 5 tablets can be followed by symptoms of intoxication in the form of drowsiness; at children the overdose by drug can be followed by concern and an acrimony, emergence of signs of anticholinergic action in the form of an ischuria, dryness in a mouth, a lock is possible.

Treatment: administration of drug should be stopped, it is necessary to wash out a stomach, to accept absorbent carbon, immediately to see a doctor.


Storage conditions:

To store in dry, protected from light, the place, unavailable to children, at a temperature below 25 °C.


Issue conditions:

According to the recipe


Packaging:

Tablets, покр. cover, 10 mg: 7, 10, 14 or 20 pieces.



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