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Ломексин®

Препарат Ломексин®. Recordati (Рекордати Лтд.) Ирландия


Producer: Recordati (Rekordati Ltd.) Ireland

Code of automatic telephone exchange: G01AF12

Release form: Soft dosage forms. Cream vaginal.

Indications to use: Trichomoniasis. Candidiasis of a vagina (Milkwoman).


General characteristics. Structure:

Active ingredient: Fentikonazola nitrate of 2,00 g

Excipients: The water purified glyceryl monostearate, dinatrium эдетат, fatty acids and a macrogoal the ether, lanolin hydrogenated almonds oil, propylene glycol, cetyl alcohol.




Pharmacological properties:

Lomeksin - antifungal drug of a broad spectrum of activity for topical administration in gynecology. Fentikonazol (active ingredient of Lomeksin) is to synthetic derivatives of an imidazole (its racemic mix in the form of nitrate salt of a fentikonazol). Renders local fungicidal and a fungistasis. Possesses also antibacterial and antiinflammatory action. The mechanism of action consists in inhibition of synthesis of the ergosterol regulating permeability of a cellular membrane of mushrooms. It is active concerning barmy mushrooms of Candida spp. (including Candida albicans) and gram-positive bacteria (Staphylococcus aureus, Streptococcus spp.), and also concerning Trichomonas vaginalis. Unlike other known azolny connections (in particular, an ekonazola, Miconazolum and a ketokonazol) фентиконазол biosynthesis of Candida spp proteases inhibits. At concentration below the minimum overwhelming concentration - from 0,25 to 16 mkg/ml. This action does not depend on the size of anti-mycotic activity and is caused by inhibition of one of modes of formation of proteolytic enzymes drozhzhepodobny mushrooms.


Indications to use:

Vulvovaginal candidiasis, vaginal trichomoniasis.


Route of administration and doses:

Cream (about 5 g) is entered deeply into a vagina in a prone position, 1 time a day, before going to bed or, if necessary, by 2 times a day - in the morning and in the evening. Treatment is carried out to absolute clinical recovery.

In order to avoid a reinfitsirovaniye it is recommended to carry out at the same time treatment of the partner by cream which pases put a balanus and a prepuce  

After each use to wash out the applicator warm water (it is not above 50 °C) with soap and to dry up.


 


Features of use:

At long use of drug development of a sensitization is possible. In this case it is necessary to stop treatment and to see the attending physician. In the absence of effect within 3 weeks of therapy treatment it is necessary to stop and specify the diagnosis.

It is impossible to appoint drug during periods. It is reasonable to begin a course of treatment after periods.

Due to the insufficiency of data of safe use of drug during the periods of pregnancy and a lactation, use of drug during these periods is not recommended.


Side effects:

Allergic reactions: seldom - urticaria, rash, an erythema. Local reactions: burning, an itch, irritation in the place of use of drug. Lomeksin, as a rule, is well had, side effects have tranzitorny character and do not demand drug withdrawal.


Interaction with other medicines:

It is not known.


Contraindications:

Hypersensitivity to drug, pregnancy and a lactation.


Overdose:

Due to low extent of absorption in a system blood stream the overdose is improbable.


Storage conditions:

To store at a temperature not above 30 °C. To store in the place, unavailable to children.


Issue conditions:

According to the recipe


Packaging:

Cream of vaginal 2%

On 78 g of cream in an aluminum tuba with the screwing-up cover.
One tuba with the doser placed in a transparent plastic case and with the application instruction in a cardboard pack.



Similar drugs

Препарат Ломексин®. Recordati (Рекордати Лтд.) Ирландия

Ломексин®

Anti-mycotic action (antifungal).





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