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medicalmeds.eu Medicines Antiviral means. Ациклостад® cream

Ациклостад® cream

Препарат Ациклостад® крем. Stada Arzneimittel ("ШТАДА Арцнаймиттель") Германия


Producer: Stada Arzneimittel ("STADA Artsnaymittel") Germany

Code of automatic telephone exchange: D06BB03

Release form: Soft dosage forms. Cream.

Indications to use: Genital herpes.


General characteristics. Structure:

Active agent: Acyclovir of 50 mg; Excipients: Dimetikon of 3 mg, polyethyleneglycol of a glitserol stearate of 50 mg, cetyl alcohol of 15 mg, paraffin of liquid 50 mg, propylene glycol of 150 mg, vaseline of white 90 mg, the water purified 592 mg.

Description: Homogeneous mass of white or almost white color.




Pharmacological properties:

The acyclovir is active concerning Herpes simplex 1 and 2 of types, the Varicella zoster virus, Epstein's virus Barre and cytomegaloviruses. The thymidinekinase of the cells infected with a virus through a number of consecutive reactions actively will transform an acyclovir to mono - di - and acyclovir triphosphate. The last interacts with virus DNA - a polymerase and is built in DNA which is synthesized for new viruses. Thus, "defective" virus DNA forms that leads to suppression of replication of new generations of viruses.

Pharmacokinetics. At local use it is practically not soaked up through the injured skin, does not get to a system blood stream.


Indications to use:

Herpes simplex of skin of lips and genital herpes.


Route of administration and doses:

To outwardly apply a thin film of cream on an affected area of skin of 5 times a day, every 4 hour. Use a cotton plug with which cause the necessary amount of cream sufficient for a covering of an affected area of skin. When putting the drug Atsiklostad® you watch that cream covered not only places with visible signs of defeat by herpes (bubbles, swellings, reddenings), but also the neighboring sites of skin. If drug is applied with hands, then it is necessary to wash up carefully hands before and after the procedure of treatment to prevent possible additional infection of affected areas of skin (for example, bacteria) or, respectively, transfer of viruses on yet not infected sites of a mucous membrane and skin. Treatment duration by the drug Atsiklostad® is established by the doctor. As a rule, the period of treatment makes 5 days, in some cases treatment should be continued until bubbles do not become covered by a crust or will not heal. However duration of treatment should not exceed 10 days.


Features of use:

Previously consult to your attending physician if you lowered immunity. It is already necessary to apply to achievement of the best effect of Atsiklostad® at an early stage of a disease, i.e. at once after detection of the first symptoms of herpes (burning, an itch, discomfort, reddening). Strictly observe the mode of purpose of the drug Atsiklostad® ordered by the doctor. During all course it is not necessary to stop treatment of earlier put term independently. In case of disturbance of the scheme of drawing, it is necessary to continue treatment according to appointed (but do not use cream more often than it is necessary also thicker layer). Cutaneous drawing cream should not be applied on mucous membranes of an oral cavity, a nose, eyes and a vagina. Ациклостад® does not prevent transfer of herpes sexually therefore during treatment it is necessary to abstain from sexual contacts, even in the absence of clinical manifestations. Drug Atsiklostad® use can lead (cream) for treatment of a herpes simplex of generative organs or proctal area along with use of latex condom to decrease in durability of condom in connection with existence in composition of medical cream of paraffin and vaseline.


Side effects:

At approach of any adverse effects which are not noted in this insert we ask to inform on it your doctor. After use of the drug Atsiklostad® the temporary burning sensation or prickings on the processed sites of skin can be noted. Reddening, dryness or a peeling of the leather processed by drug was sometimes observed. There are a morbidity, an itch, skin rash and a vulvitis. There are rare messages on allergic reactions on skin (contact dermatitis) of the drugs appearing after use containing an acyclovir. In most cases by tests for allergic reactions it is revealed that the specified skin reactions were caused rather by the ingredients which are a part of cream than active agent an acyclovir. The possible reason of reactions can consist also in contact dermatitis which is suffered by the patient, especially at expressiveness of these phenomena on the sites of skin which are not covered with cream.


Interaction with other medicines:

Strengthening of effect is noted at co-administration of immunostimulators.


Contraindications:

Hypersensitivity to an acyclovir or any other ingredient of drug.



Storage conditions:

At a temperature not above 25 °C, in the place, unavailable to children.


Issue conditions:

Without recipe


Packaging:

External use cream in tubas on 2 or 5 g; each tuba together with the application instruction is placed in a cardboard pack.



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