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medicalmeds.eu Medicines All-tonics and adaptogens. Melaksen

Melaksen

Препарат Мелаксен. Unipharm, Inc («Юнифарм») США


Producer: Unipharm, Inc (Yunifarm) of the USA

Code of automatic telephone exchange: N05CH01

Release form: Firm dosage forms. Tablets.

Indications to use: Sleep disorders.


General characteristics. Structure:

Active agent: melatonin of 3 mg
Excipients: calcium hydrophosphate, cellulose microcrystallic, magnesium stearate. Cover: talc, shellac, isopropanol.

Description: round, biconvex tablets, coated from color, white to white with a yellowish shade, from a dividing risky on the one hand tablet.




Pharmacological properties:

Is a synthetic analog of hormone of strobiloid gland (epiphysis). Normalizes circadian rhythms. The dream wakefulness, daily changes of locomotory activity and body temperature regulates a cycle. Contributes to normalization of a night dream (accelerates backfilling, improves quality of a dream, reduces number of night awakenings, improves health after morning awakening, does not cause a feeling of slackness, weakness and fatigue when awakening, dreams become brighter and emotionally rich).

Adapts an organism to bystry change of time zones, reduces stressful reactions.

Shows the immunostimulating and expressed antioxidant properties.

Slows down secretion of gonadotrophins, to a lesser extent – other hormones of an adenohypophysis - corticotropin, thyrotropin and Somatotropinum.

Does not cause accustoming and dependence.

Pharmacokinetics. At intake it is quickly and completely adsorbed, easily passes gistogematichesky barriers, including a blood-brain barrier. Has a short elimination half-life.


Indications to use:

- as a hypnagogue

- as an adaptogen for normalization of biological rhythms.


Route of administration and doses:

Inside. The adult on ½-1 to a tablet in 30-40 minutes before going to bed once a day.

As an adaptogen when changing time zones: in 1 day prior to flight and in the next 2-5 days on 1 tablet in 30–40 minutes prior to a dream. The maximum daily dose to 2 tablets a day.


Features of use:

During treatment it is necessary to refrain from driving of transport and occupations potentially dangerous types of activity demanding the increased concentration of attention and speed of psychomotor reactions. It is necessary to inform the women wishing to become pregnant on existence at drug of weak contraceptive action. To avoid bright lighting.


Side effects:

Allergic reactions to drug components, hypostases in the first week of reception are possible. Headache, nausea, vomiting, diarrhea, morning drowsiness.


Interaction with other medicines:

Strengthens effect of the drugs oppressing the central nervous system and beta-blockers. It is not recommended to accept together with hormonal medicines.

It is incompatible with MAO inhibitors, glucocorticosteroids and cyclosporine.


Contraindications:

Hypersensitivity, the expressed renal failure, autoimmune diseases, leukosis, lymphoma. Allergic reactions, lymphogranulomatosis, myeloma, epilepsy, diabetes mellitus, chronic renal failure, pregnancy and period of a lactation.


Overdose:

At accidental overdose: gastric lavage, symptomatic therapy. Strengthening of expressiveness of side effects.


Storage conditions:

Term godnosti:4 years. Not to use upon termination of a period of validity. In the dry place at a temperature of 10-30 °C. To store in the place, unavailable to children.


Issue conditions:

Without recipe


Packaging:

Tablets are coated.

On 30 or 60 tablets in a white bottle from polyethylene of high density with the screwing-up polyethylene cover and the safety valve from a foil. On a bottle paste the label, a bottle cover with polyethylene film and together with the application instruction place in a cardboard pack.

On 12 tablets in the blister from an aluminum foil / PVC. On one or two blisters together with the application instruction place in a cardboard pack.



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