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medicalmeds.eu Medicines Spasmolysants in a combination with analgetics. Bioralgin

Bioralgin

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Producer: CJSC Biofarm Russia

Code of automatic telephone exchange: A03DA02

Release form: Firm dosage forms. Tablets.

Indications to use: Pain syndrome. Renal colic. Intestinal colic. Dysmenorrhea. Neuralgia. Ischialgia. Mialgiya.


General characteristics. Structure:

Active agents - metamizole sodium of 500 mg, a pitofenona a hydrochloride - 5 mg, a fenpiveriniya bromide - 0,1 mg.

Excipients: lactose, potato starch, Natrii hydrocarbonas, talc, magnesium stearate.




Pharmacological properties:

The combined drug. Metamizol possesses analgetic, febrifugal and weak antiinflammatory action. Petofenona a hydrochloride has direct myotropic effect on smooth muscles of internals. Fenpiveriniya bromide due to holinoblokiruyushchy action makes the additional weakening impact on smooth muscles. The combination of three components of drug leads to mutual strengthening of their pharmacological action which is expressed in pain relief, relaxation of unstriated muscles, decrease in the increased body temperature.


Indications to use:

Poorly or moderately expressed pain syndrome at spasms of smooth muscles of internals - renal colic, spasms of an ureter and a bladder, bilious colic, enterospasms, a dysmenorrhea and other spastic conditions of internals. It can be used for a short-term symptomatic treatment at joint pains, neuralgia, an ischialgia, a mialgiya. As supportive application can be applied to reduction of pains after surgical and diagnostic interventions. If necessary drug can be used for decrease in the increased body temperature at catarrhal and other infectious and inflammatory diseases.


Route of administration and doses:

Adults and children are more senior than 15 years 1-2 tablets 2-3 times a day. Drug should be used after food, washing down with water. Daily dose of 6 tablets. Duration of reception is no more than 5 days. Increase in a daily dose of drug or duration of treatment are possible only under control of the doctor. Children - only on doctor's orders. A dosage for children of 6-8 years - on a half of a tablet, 9-12 years - on three quarters of a tablet, 13-15 years - on one tablets 2-3 times a day. Other modes of a dosage are possible only after consultation with the doctor.


Features of use:

With care and under control of the doctor patients should use drug with an abnormal liver function or kidneys, tendency to hypotonia, a bronchospasm, and also at the increased individual sensitivity to non-steroidal anti-inflammatory drugs or non-narcotic analgesics. At long use of drug (more than a week) control of a picture of peripheral blood and a functional condition of a liver is necessary. Metabolites of drug can sometimes paint urine in red color. Drug can influence a psychophysical condition of patients at a concomitant use with alcohol and means, the oppressing TsNS.


Side effects:

In therapeutic doses drug is usually well transferred. Allergic reactions (skin rash, an itch, very seldom acute anaphylaxis), burning sensation in epigastric area, dryness in a mouth, a headache, dizziness, a lowering of arterial pressure, tachycardia, cyanosis are sometimes possible. At long reception development of thrombocytopenia, a leukopenia, agranulocytosis is possible. At tendency to a bronkhospazum provoking of an attack is possible.


Interaction with other medicines:

Simultaneous use of drug with other non-narcotic analgesics can lead to mutual strengthening of toxic action. Tricyclic antidepressants, contraceptives for intake, Allopyrinolum break metabolism of metamizol in a liver and increase its toxicity. Barbiturates, phenylbutazone and other inductors of microsomal enzymes of a liver weaken effect of metamizol. Simultaneous use with cyclosporine reduces the level of the last in blood. Sedatives and tranquilizers strengthen the anesthetizing effect of drug. In need of simultaneous use of the specified and other medicines it is necessary to consult with the doctor.


Contraindications:

Hypersensitivity to pyrazyl ketone derivatives (Butadionum, трубузон), others to drug components. The expressed disturbances of a liver or kidneys. Tachyarrhythmia. Dekompensirovanny heart failure. Closed-angle form of glaucoma. Prostatauxe. Gastrointestinal impassability and megacolon. Diseases of system of blood. Deficit glyukozo-6-fosfatdegidrogenazy. Kollaptoidny states. Pregnancy. Lactation period. Children's age up to 6 years.


Overdose:

Symptoms: vomiting, decrease in the ABP, drowsiness, confusion of consciousness, nausea, dryness in a mouth, pain in epigastric area, sweating change, an abnormal liver function and kidneys, a spasm. Treatment: the gastric lavage, purpose of absorbent carbon, if necessary carry out symptomatic therapy.


Storage conditions:

In the dry, protected from light place, at a temperature not above 25 °C.


Issue conditions:

Without recipe


Packaging:

On 10 tablets in a blister strip packaging from a film of polyvinyl chloride and aluminum foil. On 10 tablets in planimetric bezjyacheykovy packaging from aluminum foil. 2,5,10 planimetric packagings together with the application instruction place in a pack from a cardboard.



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