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medicalmeds.eu Medicines Vazodilatatora Drotaverinum

Drotaverinum

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Producer: JSC Tatkhimfarmpreparaty Russia

Code of automatic telephone exchange: A03AD02

Release form: Firm dosage forms. Tablets.

Indications to use: Peptic ulcer of a stomach. Pain syndrome. Peptic ulcer of 12 perstny guts. Cardiospasm. Syndrome of the angry intestines. Chronic gastroduodenit. Chronic cholecystitis.


General characteristics. Structure:

Active ingredient: 1 tablet contains Drotaverinum of a hydrochloride 0,04 g.




Pharmacological properties:

The medicine possessing spasmolytic, myotropic, vasodilating, hypotensive action

Myotropic spasmolysant. On chemical structure and pharmacological properties it is close to a papaverine, but possesses stronger and long action. Reduces receipt of Ca2 + in smooth muscle cells (inhibits FDE, leads to accumulation of intracellular tsAMF). Reduces a tone of unstriated muscles of internals and a peristaltics of intestines, expands blood vessels. Does not influence the autonomic nervous system, does not get into TsNS. Existence of direct influence on smooth muscles allows to use as a spasmolysant in cases when medicines from the M-holinoblokatorov group are contraindicated (closed-angle glaucoma, prostate adenoma).


Indications to use:

For prevention and treatment of the functional states and a pain syndrome connected with a spasm of smooth muscles at a chronic gastroduodenit, chronic cholecystitis, a cholelithiasis, a postcholecystectomy syndrome, a peptic ulcer of a stomach and a 12-perstny gut, kardio-and a pylorospasm, a spastic colitis. Apply also at spasms of peripheral arterial vessels, vessels of a brain, a nephrolithiasis, to weakening of reductions of a uterus and a spasmolysis of a neck of uterus at childbirth, when carrying out tool researches.


Route of administration and doses:

Inside, the adult on 40-80 mg 2-3 times a day. To children under 6 years — in a single dose of 10-20 mg, the maximum daily dose — 120 mg; 6-12 years one-time — 20 mg, the maximum daily dose — 200 mg; frequency rate of appointment — 1-2 times a day.


Features of use:

At treatment of a peptic ulcer of a stomach and a 12-perstny gut apply in combination with other antiulcerous medicines. At intravenous administration the patient has to be in horizontal position (risk of a collapse). During treatment it is necessary to abstain from driving of motor transport and occupations other potentially dangerous types of activity demanding the increased concentration of attention and speed of psychomotor reactions (during 1 h after parenteral, especially intravenous administration). At rubbing in in a gingiva, causes strong numbness which takes place on average in 30 minutes.


Side effects:

Feeling of heat, dizziness, arrhythmia, hypotension, heartbeat, perspiration, allergic dermatitis.


Interaction with other medicines:

At simultaneous use Drotaverinum can weaken protivoparkinsonichesky effect of a levodopa.


Contraindications:

Hypersensitivity to drug components, the expressed liver, renal and heart failure; AV blockade II—III Art., cardiogenic shock, arterial hypotension.



Storage conditions:

List B.: In the dry, protected from light place.


Issue conditions:

Without recipe


Packaging:

Tablets on 0,04 g. Tablets on 0,08 g.



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