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medicalmeds.eu Medicines Non-steroidal anti-inflammatory drug (NPVP). Диклофенак-Акри®

Диклофенак-Акри®

Препарат Диклофенак-Акри®. ОАО "Химико-фармацевтический комбинат "АКРИХИН" Россия


Producer: JSC Chemical and Pharmaceutical Plant AKRIKHIN Russia

Code of automatic telephone exchange: M02AA15

Release form: Soft dosage forms. Gel.

Indications to use: Bruises. Tendovaginitis. Bursitis. Pseudorheumatism. Bekhterev's disease (Ankylosing spondylarthritis). Osteoarthrosis (Остеоартит). Radiculitis. Lumbago. Ischialgia. Rheumatic diseases. Chronic arthritis. Pain syndrome.


General characteristics. Structure:

Active ingredient: 1 g of diclofenac of sodium.

Excipients: carbomer 940 or 980, diethanol amide, ethanol (the alcohol rectified), propylene glycol, a liquid paraffin, кокоилкаприлкапрат, a macrogoal цетостеарат (a macrogoal the 20th cetostearyl ether), lavender oil, orange of flowers oil (neroli oil), the water purified.




Pharmacological properties:

Pharmacodynamics. Active component diclofenac — the non-steroidal anti-inflammatory drug (NPVP) having the expressed analgeziruyushchy and antiinflammatory properties. Not selectively oppressing type cyclooxygenase 1 and 2, breaks metabolism of arachidonic acid and synthesis of prostaglandins which are the main link in development of an inflammation.

Диклофенак-Акри® it is used for elimination of a pain syndrome and reduction of puffiness. The water and ethanol basis in addition has mestnoanesteziruyushchy effect. At the recommended way of putting drug no more than 6% of diclofenac are absorbed.


Indications to use:

- a posttraumatic inflammation of soft tissues and joints, for example, as a result of stretchings, retension and bruises;
- rheumatic diseases of soft tissues (tendovaginitis, bursitis, defeat of periartikulyarny fabrics);
- inflammatory diseases of a musculoskeletal system (a pseudorheumatism, the psoriasis, juvenile chronic arthritis ankylosing a spondylarthritis);
- the pain syndrome and puffiness connected with diseases of muscles and joints (a pseudorheumatism, an osteoarthrosis, radiculitises, a lumbago, a sciatica).


Route of administration and doses:

Outwardly. To adults and children 12 years drug are more senior apply on skin 3-4 times a day and slightly rub. The necessary amount of drug depends on the size of a painful zone. The single dose of drug makes 2-4 g (that on volume is comparable according to the size of cherry or walnut). After putting drug of a hand it is necessary to wash up.

Duration of treatment depends on indications and noted effect. After 2 weeks of use of drug it is necessary to consult with the doctor.


Features of use:

Drug should be applied only on the unimpaired skin, avoiding hit on open wounds. After drawing it is not necessary to apply an occlusive bandage. It is not necessary to allow hits of drug on eyes and mucous membranes. When drawing on the big surfaces of skin the risk of development of system side effects increases for a long time.

Use at pregnancy and during breastfeeding. Drug cannot be used in the III trimester of pregnancy. Experience of use of the drug Diklofenak-Akri® in the period of a lactation is not available. Use in I and II trimesters is possible only after consultation with the doctor.


Side effects:

Local reactions: eczema, a photosensitization, contact dermatitis (an itch, reddening, puffiness of the processed site of skin; papules, vesicles, peeling).

System reactions: generalized skin rash, allergic reactions (small tortoiseshell, Quincke's disease, bronkhospastichesky reactions), photosensitization.


Interaction with other medicines:

Диклофенак-Акри® can strengthen effect of the drugs causing a photosensitization. Clinically significant interaction with other medicines is not described.


Contraindications:

Hypersensitivity to diclofenac, or to other components of drug; to acetylsalicylic acid, or to other NPVP, "aspirinovy" asthma, pregnancy (the III trimester), the lactation period, children's age (up to 6 years), disturbance of integrity of integuments.

With care. Hepatic porphyria (aggravation), digestive tract erosive cankers, heavy abnormal liver functions and kidneys, chronic heart failure, advanced age, bronchial asthma, pregnancy (I and II trimester).


Overdose:

Extremely low system absorption of active components of drug at external use makes overdose almost impossible.


Storage conditions:

Drug cannot be used after expiry date. At a temperature from 15 to 25 °C in the place, unavailable to children. A period of validity - 2 years.


Issue conditions:

Without recipe


Packaging:

Gel for external use of 1%. On 20, 30, 40 or 50 g in a tuba aluminum. Each tuba together with the application instruction is placed in a pack from a cardboard.



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