Glutargin Alkoklin, powder 1g/3g in packages No. 1kh10/1g/3g in packages No. 1х2

General characteristics. Structure:

Pharmacological properties:

Glutargin – salt of arginine and glutaminic acid. At a drunkenness stimulates utilization of alcohol in monooksigenazny system of a liver, prevents oppression of key enzyme of utilization of ethanol – alcohol dehydrogenase; accelerates an inactivation and removal of toxic products of metabolism of ethanol as a result of increase in education and oxidation of succinic acid; reduces the oppressing influence of alcohol on TsNS due to neuromediator properties of exciting glutaminic acid. Thanks to these properties Glutargin shows the anti-toxic and sobering effects.

Glutargin has also gipoammoniyemichesky and hepatoprotective properties caused by activation of processes of neutralization of ammonia in an organism, antioxidant, anti-hypoxemic and membrane stabilizing effects, positively influences processes of power supply in hepatocytes.

Glutargin does not render embriotoksichesky, gonadotoksichesky, mutagen and teratogenic effects, does not cause allergic and immunotoxic reactions.

Indications to use:

Prevention of intoxication and hepatotoxic action of alcohol. Treatment of an acute drunkenness easy and moderately severe, and also as a part of complex therapy of postintoksikatsionny frustration after acute alcoholic poisoning of heavy degree.

Route of administration and doses:

Drug is appointed the adult inside, previously having dissolved a package in ¼-½ a glass of water.

For prevention of intoxication and a hepatotoxic action of alcohol appoint 2 g (2 packages) for 1-2 h before alcohol intake or 1 g (1 package) for 1 h before alcohol intake and 1 g (1 package) during 0,5 h after alcohol intake. For treatment of an acute drunkenness easy and moderate severity appoint 1 g (1 package) 4 times in bucketed day of 1-2,5 h, in the next 2-3 days – on 1 g (1 package) 2 times a day. At a drunkenness of heavy degree Glutargin's powder is appointed on 1 g (1 package) by 2 times a day within 20 days as a part of complex therapy after a course of treatment injection drugs of Glutargin.

Features of use:

- Use during pregnancy or feeding by a breast. Safety of a clinical use of drug in I and II trimesters of pregnancy and when feeding by a breast is not investigated.

- Ability to influence speed of response at control of motor transport or other mechanisms. Does not influence.

- Children. Efficiency and safety of use of drug at children's and teenage age are not investigated.

Side effects:

The feeling of slight discomfort in digestive tract and nausea directly after drug use which pass independently can seldom be observed.

Interaction with other medicines:

Glutargin's effect on secretion of insulin increases at co-administration of Aminophyllinum. Glutargin can strengthen effect of anti-aggregation means (Dipiridamolum, etc.). Warns and weakens the neurotoxic phenomena which can arise at use of an isoniazid. Weakens effect of vinblastine.

Contraindications:

Relative contraindication are the feverish condition, a hyperexcitability, heavy disturbances of filtrational (azotovy-dividing) function of kidneys.

Overdose:

Symptoms: nausea, vomiting, abdominal pains, a liquid chair, allergic reactions, a fever, a short-term hyperthermia and/or hypotonia, excitement of the central nervous system, sleeplessness is possible. Treatment: depending on expressiveness of clinical symptomatology - reception of absorbent carbon, a symptomatic treatment, if necessary antihistaminic therapy.

Storage conditions:

To store in original packaging at a temperature not above 25 °C. To store in the place, unavailable to children.

Period of validity - 2 years.

Issue conditions:

Without recipe

Packaging:

On 3 g of powder (1 g of arginine of a glutamate) in a package (No. 1) or in the coupled packages (No. 2); on two, five or ten packages (No. 1) or on five the coupled packages (No. 2) in a box.