Xyflax

Xyflax – the pharmacological drug on the basis of vasoconstrictive substances used for treatment of cold.

Active ingredient – xylomethazolinum.

Structure and form of release

According to the instruction Ksilen is issued in the form of nasal drops.

Except active ingredient nasal drops also contain auxiliary components: chloride benzalkoniya, dinatrium эдетат, hydrophosphate sodium dodecahydrate, potassium dihydrophosphate, sodium chloride, water.

Ksilen's solution is produced in concentration 0,1% and 0,05%. In a plastic bottle (or glass) on 10 ml of this drug.

Pharmacological action of Ksilen

According to the instruction Ksilen possesses antiedematous action due to rendering local vasoconstrictive effect. When narrowing blood vessels of a mucous membrane of a nose there is a reduction of hypostasis and a hyperemia, and passability of the nasal courses is recovered that facilitates nasal breath and removes a nose congestion. Xyflax begins to have effect practically right after use, the effect remains till 10 o'clock.

As drug is used locally, it is practically not soaked up in blood. Modern methods to find its concentration in blood after use do not work well.

Indications to use

Xyflax is applied at the acute rhinitises caused by viral respiratory infections. Also drug is shown at acute allergic rhinitis, sinusitis, at average otitis (as a part of complex treatment with the purpose to reduce hypostasis of a mucous membrane of a nasopharynx). Xyflax is applied before carrying out a rinoskopiya (an endoscopic method of inspection of the nasal courses and a nasopharynx).

Contraindications

This drug is contraindicated in case of hypersensitivity to its components, at the expressed atherosclerosis, arterial hypertension, tachycardia and glaucoma.

It is contraindicated to use xyflax at patients with atrophic rhinitis, and also at patients who have in the anamnesis the performed surgeries on a meninx. Up to 6 years it is contraindicated to children to use 0,1% solution of this drug, it is necessary to use a special children's dosage (0,05% solution).

With extreme care it is necessary to apply Ksilen at patients with a diabetes mellitus, a prostate hyperplasia, a hyperthyroidism, and at coronary heart disease. In case of existence of contraindications to Ksilen it is not necessary to use independently this drug, discuss with the doctor treatment by similar medicines.

Side effect

At long (or too frequent) Ksilen's use there can be a dryness, irritation of a mucous nasopharynx (it can be shown by sneezing, burning, slime hypersecretion). There can seldom be vomiting, a headache, heartbeat, tachycardia, increase in arterial pressure, arrhythmia, a vision disorder, sleeplessness, a depression. For emergence of such side effects Ksilen's use has to be long and in the exceeded doses.

Ksilen's use at pregnancy and a lactation

Ksilen's use at pregnancy, and also during feeding by a breast is not recommended. Drug in itself has no negative effect on a fruit, but it can influence the arterial pressure of the pregnant woman, and also a tone of vessels of a placenta.

Route of administration and doses

It is necessary to dig in xyflax in each nasal course (after preliminary clarification) on 1-2 drops of 0,1% of solution (for adults and children is more senior than years) no more than 2-3 times a day.

Use of 0,05% of solution of Ksilen on 1-2 drops in each nasal course of one time a day is recommended to children of chest age and children up to 6 years.

It is not necessary to use this drug more than 3 times a day and more than 5 days.

Overdose by Ksilen

At overdose there are above described symptoms of side effects. Treatment is directed to the termination of use of drug and elimination of the arisen symptoms.

Interaction with other medicines

Xyflax cannot be used along with MAO inhibitors (monoamine oxidase), and also with tricyclic antidepressants.

Special instructions on Ksilen's use

Before a drug instillation in the nasal courses it is necessary to clear them. At chronic rhinitis unacceptably long use of Ksilen.

This drug in the recommended dosages does not exert impact on ability to manage motor transport and the work demanding the increased concentration of attention.