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Rheopyrinum

 Раствор для инъекций РеопиринRheopyrinum – the combined medicine of antiinflammatory, analgeziruyushchy and febrifugal action.

Form of release and structure

Rheopyrinum is issued in the following forms:

  • Dragee (on 10 pieces in the blister, in a cardboard pack two blisters);
  • Solution for injections (on 5 ml in an ampoule, in a cardboard pack five ampoules).

Active ingredients as a part of 1 dragee:

  • Sodium phenylbutazone – 125 mg;
  • Aminophenazonum – 125 mg.

Active ingredients as a part of 1 ml of solution:

  • Sodium phenylbutazone – 150 mg;
  • Aminophenazonum – 150 mg.

Indications to use

  • Polyneuritis, neuralgia, neuritis;
  • Retinitis, iritis, iridocyclitis;
  • Parametritis;
  • Lumbago;
  • Adnexitis;
  • Polyserositis, pericardis (at severe pain);
  • Diseases of soft extraarticular tissues and backbone with pains and the expressed inflammation;
  • Noninfectious arthritises of various origin (including gouty arthritis and acute rheumatic arthritis).

Contraindications

  • Chronic cardiomyopathy;
  • Disturbances of a heart rhythm;
  • Edematous syndrome (including in the anamnesis);
  • Heart diseases;
  • Peptic ulcer of a duodenum and stomach;
  • Diseases of bodies of system of a hemopoiesis;
  • Diseases of kidneys and liver;
  • Children's age up to 7 years;
  • Hypersensitivity to drug.

Route of administration and dosage

At rheumatic diseases Rheopyrinum is accepted inside in a dose of 4-6 dragees in days or deeply intramusculary 5 ml a day every day or every other day (solution is entered slowly (within 1-2 minutes) into a gluteus by means of a long needle).

At a parametritis and an adnexitis the drug is administered intramusculary on 5 ml by each 4-5 days before disappearance of symptoms.

For children aged from 7 up to 14 years the recommended dose of Rheopyrinum makes 0,5-1 dragees or 0,5-1 ml of solution 3 times a day every day or every other day.

Side effects

  • Alimentary system: perhaps – vomiting, nausea, increase of a chair, erosive cankers of digestive tract, pain in epigastriums;
  • Cardiovascular system: tachycardia;
  • Central nervous system: drowsiness, dizziness;
  • Urinary system: a hamaturia, a glucosuria, a renal tubular necrosis (at prolonged treatment in high doses);
  • Metabolism: delay of sodium and water;
  • System of a hemopoiesis: seldom – anemia, thrombocytopenia, a leukopenia; at prolonged treatment by high doses of drug – an agranulocytosis;
  • Allergic reactions: urticaria, itch, skin rash;
  • Local reactions: pain in the place of an injection, sterile abscess in an injection site.

Special instructions

To children Rheopyrinum is appointed in exceptional cases, in the conditions of a hospital and only under control of the doctor and at regular tracking of a picture of peripheral blood, function of a liver and composition of urine.

In case of suspicion of epilepsy parenteral administration of Rheopyrinum is not recommended.

At prolonged use it is necessary to control number of leukocytes every week.

Medicinal interaction

At simultaneous use drug weakens action of Phenytoinum, cephalosporins, Imipraminum and griseofulvin.

Rheopyrinum strengthens effect of anticoagulants, barbiturates, streptocides and peroral hypoglycemic means.

Terms and storage conditions

To store at a temperature of 15-25 °C. To protect from children. A period of validity – 3 years.

 
 
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