Agony (agonia; Greek agonia – fight, an agony) – a terminal state which precedes approach of death and is characterized by deep disturbance of functions of the highest departments of a brain, especially bark of hemicerebrums. Along with it excitement of the centers of a myelencephalon is observed.

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The weight of a human brain makes about 2% of all body weight, however it consumes about 20% of the oxygen coming to blood. This fact does a human brain extremely susceptible to the damages caused by shortage of oxygen.