Family endogenous gipertriglitseridemiya
Contents:
Description:
The family endogenous gipertriglitseridemiya meets about 1 of 300 people and is characterized by increase in the LPONP level (the IV giperlipoproteidemiya). Level of triglycerides usually makes from 200 to 500 mg/dl (2,3-5,7 mmol/l), the content of cholesterol normal or is slightly increased, and the level of LPNP cholesterol is lowered.
Symptoms of the Family endogenous gipertriglitseridemiya:
At a family endogenous gipertriglitseridemiya Vtipa giperlipoproteidemiya with the content of triglycerides more than 1000 mg/dl (11,3 mmol/l) and a hypercholesterolemia is found. At this option of a family endogenous gipertriglitseridemiya the risk of coronary heart disease is considerably increased. Besides, there is a danger of development of acute pancreatitis.
Reasons of the Family endogenous gipertriglitseridemiya:
It is transferred on autosomal dominantly type, meets frequency of 1:500. At heterozygous find 2-and 3-fold increase in content of cholesterol and LPNP in a blood plasma.
Treatment of the Family endogenous gipertriglitseridemiya:
Treatment consists in purpose of a hypocholesteric diet, and also the pitches connecting bile acids (холестирамин or колестипол), and GMG-KOA-reduktazy inhibitors (ловастатин, провастатин, симвастатин).
