Agammaglobulinemia
Contents:
- Description
- Agammaglobulinemia symptoms
- Agammaglobulinemia reasons
- Treatment of the Agammaglobulinemia
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Description:
Agammaglobulinemia (a synonym a syndrome of deficit of antibodies) — absence or sharp decrease in content of gamma-globulins in a blood plasma. At the same time there is impossible a development of necessary quantity of antibodies in this connection patients with an agammaglobulinemia are extremely subject to infectious diseases.
Agammaglobulinemia symptoms:
Clinically the agammaglobulinemia is characterized by predisposition to bacterial infections at the normal resilience against a viral infection. Infectious diseases at an agammaglobulinemia proceed is long, with frequent aggravations and heavy complications. The diagnosis is established by identification of low level of gamma-globulins at a plasma electrophoresis. The forecast is adverse.
Agammaglobulinemia reasons:
Distinguish the hereditary and acquired agammaglobulinemia. The hereditary agammaglobulinemia — a rare disease, happens at boys (usually comes to light aged up to 6 years); it is connected with an underdevelopment of lymphoid and plasmatic fabric and loss by an organism of ability of synthesis of gamma-globulins. The acquired agammaglobulinemia occurs at people of both sexes aged from 7 up to 70 years; in some cases the disease is a consequence of the postponed serious infectious diseases or arises at malignant new growths of the lymphoid device (a chronic lymphoid leukosis, etc.), nefroza, etc.
Treatment of the Agammaglobulinemia:
Treatment is carried out under control of the doctor: administration of gamma-globulin once a month on 0,1 g on 1 kg of body weight intramusculary; hemotransfusion.