Hemosorption

Description:

Hemosorption (from Greek haema blood + lat. to absorb sorbere) — the treatment method directed to removal from blood of various toxic products and regulation of a hemostasis by contact of blood with a sorbent out of an organism. It is a kind of process of sorption at which particles of the absorbed substance and absorbers enter chemical interactions. Hemosorption — a method of extrarenal clarification of blood from toxic substances by adsorption of poison on a sorbent surface. As sorbents absorbent carbon (gemokarboperfuziya) or the ion-exchange resins intended for clarification of blood from certain groups of chemicals use.

The indication to hemosorption are many acute poisonings with medicines (barbiturates, Elenium, Noxyronum) and chemical poisons (chlorinated hydrocarbons, organophosphorous connections); the acute damages of a liver proceeding with the expressed intoxication, especially in a stage of a prekoma and a coma. Besides, hemosorption as an additional method of treatment can be applied at patients with a system lupus erythematosus, cold urticaria, psoriasis, food polyallergy, bronchial asthma, a family lipidemia (cholesterinemia).

The device for hemosorption represents the column filled with a sorbent which is connected by means of tubular highways to the patient's vessels. Blood on system of tubular highways is pumped over by means of the pump through a column. For the prevention of an air embolism in tubular highways there are expansions — bubble cameras in which the movement of blood is slowed down and there is department of vials of air. Branches for connection of the manometers measuring blood pressure in tubular highways before passing of a column with a sorbent that is necessary for identification of a possible blood coagulation in a column are built in bubble cameras. All accessories to G. release sterile, ready for immediate use.

At hemosorption complications, in particular decrease in the ABP, the expressed fever (the pyrogenic reaction), bleeding, an air embolism, an embolism a sorbent are possible.

Main data.
The method is based on two properties of a sorbent:
adsorptions (fixing of a molecule of substance on an absorber surface);
absorption (fixing of substance in volume of an absorber).

Fixing of chemical agents happens due to formation of covalent or ionic bonds of substance to active groups of an absorber.