The vaccine is parotitis cultural live

General characteristics. Structure:

Active ingredient: not less than 20 000 (4,3 lg) fabric cytopathic doses (TTsD50) of a virus of parotitis.

Excipients: the stabilizer - mix of aqueous solution LS-18 * and 10% of solution of gelatin, Gentamycini sulfas.

Note. * Structure of aqueous solution of LS-18: sucrose, lactose, sodium glutaminovokisly, glycine, L-proline, Hanks dry mix with phenolic red, water for injections.

The vaccine is parotitis cultural live, lyophilisate for preparation of solution for hypodermic introduction, Leningrad - 3 on primary culture of cells of embryos of quails prepares by method of cultivation of an attenuirovanny virus strain of parotitis.

Indications to use:

Prevention of epidemic parotitis, since age of 12 months.

According to the National calendar of preventive inoculations vaccination is carried out at the age of 12 months and 6 years to the children who did not have epidemic parotitis twice.

The emergency prevention is carried out to children from 12 months, to the teenagers and adults who had contact with sick parotitis, not having epidemic parotitis or earlier not imparted against this infection. In the absence of contraindications the vaccine is entered no later than in 72 h from the moment of contact with the patient.

Route of administration and doses:

Just before use the vaccine is parted with solvent for clumsy, parotitis and parotitis коревой cultural live vaccines (solvent is called further) at the rate of 0,5 ml of solvent on one inoculative dose of a vaccine.

The vaccine has to be dissolved completely within 3 min. The dissolved vaccine - transparent liquid of pink color.

The vaccine and solvent in ampoules with the broken integrity, marking are not suitable for use, and also at change of their physical properties (color, transparency, etc.), expired or incorrectly stored. Opening of ampoules and the procedure of vaccination are carried out at strict observance of rules of an asepsis and antiseptics.

Ampoules with a vaccine and solvent on site of a cut process 70 ° alcohol and break off, without allowing at the same time hit of alcohol in an ampoule.

For cultivation of a vaccine select all necessary volume of solvent and transfer it to an ampoule with a dry vaccine. After hashing the vaccine is gathered other needle in the sterile syringe by which further carry out vaccination. The vaccine is entered subcutaneously of 0,5 ml under a shovel or to the area of a shoulder (on border between the lower and average third of a shoulder from the outer side), previously having processed leather in a vaccine 70 injection site ° alcohol.

The dissolved vaccine is used immediately and is not subject to storage. The carried-out vaccination is registered in the established registration forms with the indication of the name of drug, date of vaccination, a dose, the manufacturing enterprise, number of a series, period of validity, reaction to an inoculation.

Features of use:

Considering a possibility of development of allergic reactions of immediate type (an acute anaphylaxis, a Quincke's edema, a small tortoiseshell) at especially sensitive persons, for vaccinated it is necessary to provide medical observation within 30 min.

Venues of inoculations have to be provided with means of antishock therapy.

Use at pregnancy and during breastfeeding. Performing vaccination is contraindicated.

Side effects:

At the majority imparted vaccinal process proceeds asymptomatically. After introduction of a vaccine the following side reactions of various degree of manifestation can be observed:

Often (1/10 - 1/100):

• with 5 on 15 days – short-term slight increase of body temperature, the catarral phenomena from a nasopharynx (an easy hyperemia of a pharynx, rhinitis). At mass use of a vaccine fervescence above 38,5 °C should not be more, than at 2 percent vaccinated. Fervescence above 38,5 °C in the postvaccinal period is the indication to purpose of antipyretics.

Seldom (1/1000 - 1/10000):

• in the first 48 h after an inoculation the local reactions which are expressed in a dermahemia and poorly expressed hypostasis in a vaccine injection site which pass without treatment;
• with 5 on 42 days – insignificant increase in parotid sialadens the proceeding 2-3 days;
• concern, slackness, sleep disorder.

Very seldom (<1/10000):

• in the first 24-48 h – the allergic reactions arising at persons with the changed reactivity;
• in 2-4 weeks – it is good-quality the proceeding serous meningitis. Each case of serous meningitis demands differential diagnosis;
• painful short-term hypostasis of testicles.

At emergence of the side effects which are not described in the instruction, the patient should report about them to the doctor.

Interaction with other medicines:

Vaccination against parotitis can be carried out at the same time (in one day) with other calendar inoculations (against measles, a rubella, poliomyelitis, hepatitis B, whooping cough, diphtheria, tetanus, flu, a hemophilic infection) on condition of introduction to different body parts or not earlier than in 1 month after the previous inoculation.

After administration of drugs of immunoglobulin of the person of an inoculation against parotitis are carried out not earlier than in 2 months.

After introduction of a parotitis vaccine the drugs of immunoglobulin can be administered not earlier than in 2 weeks; in case of need uses of immunoglobulin before this term vaccination against parotitis should be repeated.

Contraindications:

Anaphylactic reactions or severe forms of allergic reactions to aminoglycosides (Gentamycini sulfas), chicken and/or quail eggs.

Primary immunodeficiency, malignant diseases of blood and new growth. Strong reaction (rise in temperature is higher 40 With, a hyperemia and/or hypostasis more than 8 cm in the diameter in a vaccine injection site) or a complication to the previous introduction parotitis or parotitis коревой vaccines.

Pregnancy and period of breastfeeding.

Acute diseases or exacerbation of chronic diseases.

Note. HIV infection is not a contraindication to vaccination.

Storage conditions:

In the place protected from light, at a temperature of 4-8 °C and humidity no more than 60%. Storage is allowed at a temperature of-20-24 °C. To store in the place, unavailable to children. A period of validity - 2 years.

Issue conditions:

According to the recipe

Packaging:

Lyophilisate for preparation of solution for hypodermic introduction. On 1 or 2 doses in an ampoule. In a pack of 10 ampoules with the application instruction and an insert with number of the stacker.