Immunoglobulin anti-staphylococcal person

General characteristics. Structure:

Active ingredients - specific antibodies, active in relation to staphylococcal alpha exotoxin. One dose of drug contains not less than 100 ME of anti-alphastaphylolysin.

excipients - glycine (glycine, the aminoacetic acid), sodium chloride.

Main properties: drug is immunological the active protein fraction allocated from serum or the blood plasma of the person checked for lack of antibodies to VICh-1, VICh-2, to a virus of hepatitis C and a surface antigen of a virus of hepatitis B, cleared and concentrated by a fractionation method the spirtovodny besieging solutions to the virus inactivation which passed a stage solvent-detergentnym with method. Transparent or slightly opalescent, colourless or yellowish liquid. In the course of storage emergence of the insignificant deposit disappearing when stirring is allowed. Protein content in 1.0 ml of drug from 0:09 g to 0:11 g. Drug does not contain preservative and antibiotics.

Pharmacological properties:

Drug contains in high concentration of an antibody to staphylococcal alpha exotoxin. Is immunoglobulin of the directed action: compensates for the deficiency of specific neutralized antibodies of an organism.

Indications to use:

Drug is used for the purpose of treatment of diseases of a staphylococcal etiology at children and adults.

Route of administration and doses:

Immunoglobulin is entered intramusculary.

In case of a generalizirovanny staphylococcal infection the minimum single dose of drug makes 5 ME anti-alphastaphylolysins on 1 kg of body weight (for children up to 5 years a single dose - not less than 100 ME). At the slight localized diseases the minimum single dose of drug – not less than 100 ME. Injections carry out daily or every other day depending on disease severity, a condition of sick and therapeutic effect. A course of treatment – 3 - 5 injections.

Features of use:

It is forbidden to administer the drug intravenously!

 And on an extent of the next 8 days purpose of antihistaminic drugs is recommended to the patients having allergic diseases, or having a serious allergic illness in the anamnesis in day of administration of immunoglobulin. To persons with immune general diseases (diseases of blood, connecting fabric, nephrite, etc.), it is necessary to enter immunoglobulin against the background of the corresponding therapy.

Side effects:

Reactions to administration of immunoglobulin, as a rule, are absent. In rare instances there can be local reactions in the form of a hyperemia and temperature increase to 37.5 ^{° C} on an extent of the first two days after administration of drug. Drug with the changed reactivity can cause reactions of an allergy of different type in certain people, and in exclusively exceptional cases - an acute anaphylaxis. In this regard the persons who received drug have to be under medical supervision on an extent of 30 minutes.

Interaction with other medicines:

The combination with other specific medicines is possible.

Contraindications:

Administration of immunoglobulin is contraindicated to the persons having heavy allergic reactions to introduction of proteinaceous blood preparations of the person in the anamnesis. In case of heavy sepsis the only contraindication is the acute anaphylaxis on blood preparations of the person in the anamnesis.

Overdose:

It was not studied.

Storage conditions:

In the dry, protected from light place at a temperature from 2 °C to 8 °C. To store in the place, unavailable to children.

Issue conditions:

According to the recipe

Packaging:

On 100 MO (1 dose) in an ampoule. On 3, 5 or 10 ampoules in a pack.