Asparkam, tab. No. 10, No. 50

General characteristics. Structure:

Active agent: 1 tablet contains - 0,175 g of magnesium of asparaginate and potassium of asparaginate; excipients: potato starch or starch corn, calcium stearate, talc before receiving a tablet weighing 0,5 g.

Pharmacological properties:

The asparkam belongs to the means regulating metabolic processes. It is hydrolyzed in an organism to aspartic acid. Asparaginate transfers potassium ions and magnesium and promotes their penetration into intracellular spaces. The potassium ion participates in transfer of nervous excitement, provides depolarization of postsynaptic membranes, participates in maintenance of isotonicity of cells. Maintains automatism of a cardiac muscle, causes delay of a cordial rhythm, is an antagonist of calcium, reduces toxicity of cardiac glycosides, at the same time without changing their positive ionotropny action, moderately increases a diuresis. The ion of magnesium promotes manifestation of therapeutic effect of drug. Under the influence of drug the hypoxemic disturbances of an etabolizm of a myocardium connected with deterioration in coronary circulation decrease. The asparkam stops, but urezhat ventricular premature ventricular contraction and a paroxysmal ciliary arrhythmia at patients with a myocardial infarction and stenocardia at any stage of a circulatory unefficiency more often. Increase in a stroke output of blood circulation at use of an asparkam is observed against the background of normalization of content of potassium in erythrocytes and disappearance or considerable reduction of the broken rhythm of cordial activity.

Indications to use:

The asparkam is appointed at the disturbances of a heart rhythm caused by toxic effect of drugs of a foxglove, recently arisen ventricular premature ventricular contraction, atrial fibrillation paroxysms. Use of an asparkam is shown at a chronic circulatory unefficiency, coronary heart disease, depressed cases of various genesis. Appoint also at intolerance of drugs of a foxglove. At a combination of an atrioventricular block to disturbance of a heart rhythm drug is not appointed.

Route of administration and doses:

Drug orally in a medical dose is appointed on 2 tablets by 3 times a day; a preventive and maintenance dose - on 1 tablet 3 times a day. In more hard cases (at disturbances of coronary circulation, intolerance of drugs of a foxglove, etc.) - on 3 tablets 3 times a day. 2-3 weeks later reduce a dose to 1 tablet 2-3 times a day.

Side effects:

The patients having anacid gastritis or cholecystitis can have unpleasant feelings or burning in an anticardium.

Interaction with other medicines:

The asparkam lowers sensitivity to cardiac glycosides.

Contraindications:

Acute and chronic renal failure, hyperpotassemia, hyper-magniyemiya, predisposition or existence of the raised organism allergization. Disturbances of atrioventricular conductivity of the II-III degree.

Issue conditions:

According to the recipe