ABSORBABLE GELATIN SPONGE ® (HAEMOSTATIC SPONGE ®)

General characteristics. Structure:

Deystvuyushche substance: 1 bottle contains native plasma from donor blood of the person or dry plasma – 10 ml, 4 (aminomethyl) of the benzoic acid (Ambenum) – 0,05 g, Calcii chloridum of hexahydrate of-0,05 g.

Main physical and chemical properties: The lyophilized hydroscopic porous weight white with yellowish or color, yellow with a brown shade, with a light specific smell;

Pharmacological properties:

The sponge ^{гемостатическая®} belongs to means which influence system of a blood coagulation. At topical administration the drug containing fibrin and thrombin activates blood coagulation processes, stops capillary and parenchymatous bleedings. Ambenum has anti-fibrinolitic effect, the fibrinolysis by competitive inhibition of plazminogenaktiviruyushchy enzyme and oppression of formation of plasmin oppresses.

Pharmacokinetics. It was not studied.

Indications to use:

Local capillary and parenchymatous bleedings, bleedings from bones, muscles and fabrics, the bleedings localized on a body surface or in his cavities. Nasal, gingival bleedings and bleedings at patients with a Werlhof's disease, leukoses, hemorrhagic trombotsitopatiya, Osler's syndrome - Randyu, cirrhosis, chronic nephrite.

Route of administration and doses:

The sponge ^{гемостатическую®} is applied locally. Before use drug is got from a bottle the sterile tool. The single dose depends on character and expressiveness of bleeding: apply from 1/4 parts of the Sponge to 3–4 Sponges. After drainage the bleeding area is tamponed Sponge pieces гемостатической®, pressing down them for 3–5 minutes a sterile gauze ball. At the expressed bleedings the Sponge ^{гемостатическую®} is pressed to the bleeding surface a surgical instrument with the flat polished surface in order to avoid loss of a part of the Sponge ^{гемостатической®} as it happens in case of use of a gauze ball. For soft, longer tamponade the Sponge ^{гемостатическая®} can be placed in a gauze tampon. Tampons are taken in a day.

Features of use:

Apply locally. Drug is also used at increase in fibrinolitic activity.

Side effects:

It is not revealed.

Interaction with other medicines:

It is not established.

Contraindications:

 Are not established.

Overdose:

It is not established.

Storage conditions:

Store in dry, protected from light and the place, unavailable to children, at ^{a temperature not above 25 °C}. A period of validity – 2 years.

Issue conditions:

According to the recipe

Packaging:

On 0,8 g of drug in the bottle packed into a pack.