ЗОСТЕВИР®

General characteristics. Structure:

Active ingredients - specific antibodies to the Varicella Zoster virus.

the stabilizer - glycine (glycine, the aminoacetic acid).

Main properties: drug is immunological the active protein fraction allocated from serum or the blood plasma of the person checked for lack of antibodies to VICh-1, VICh-2, to a virus of hepatitis C and a surface antigen of a virus of hepatitis B, cleared and concentrated by a fractionation method the spirtovodny besieging solutions to the virus inactivation which passed a stage solvent-detergentnym with method. Transparent or with insignificant opalescence, colourless or yellowish liquid. At storage emergence of the insignificant deposit disappearing when stirring is possible. Drug does not contain preservative and antibiotics, in it there are no antibodies to VICh-1, VICh-2, a virus of hepatitis C and a surface antigen of a virus of hepatitis B.

Pharmacological properties:

The operating basis of drug are immunoglobulins, including immunoglobulin G, active to the Varicella Zoster virus. Specific effect of drug is caused by virusneytraliziruyushchy activity of antibodies. Besides immunoglobulin G causes immunomodulatory effect, influencing different links of immune system of the person, and increasing nonspecific resistance of an organism.

Indications to use:

Drug is used for treatment of patients with a herpes infection with defeat of the nervous system caused by the Varicella Zoster virus.

Route of administration and doses:

Immunoglobulin is entered intramusculary.

The scheme of treatment of patients with a herpes infection with defeat of the nervous system caused by the Varicella Zoster virus provides 5-times introduction on 3 ampoules (4.5 ml) of immunoglobulin with a daily interval once a day. The course of treatment immunoglobulin makes 10 days.

Features of use:

It is forbidden to administer the drug intravenously!

Side effects:

Reactions to administration of immunoglobulin , as a rule, are absent. In rare instances local reactions in the form of a hyperemia and temperature increase to ^{37.5 0C} within the first days can develop. Drug with the changed reactivity can cause reactions of an allergy of different type in individuals, and in exclusively exceptional cases - an acute anaphylaxis. In this regard persons who received drug have to be under medical observation within 30 minutes.

Contraindications:

Administration of immunoglobulin is contraindicated to the persons having heavy allergic reactions to introduction of proteinaceous blood preparations of the person in the anamnesis. And in the next 3 days antihistaminic drugs are recommended to the patients having allergic diseases or having them in the anamnesis in day of administration of immunoglobulin. To the persons suffering from immune general diseases (diseases of blood, connecting fabric, nephrite, etc.), it is necessary to enter immunoglobulin against the background of the corresponding therapy.

Storage conditions:

In the dry, protected from light place at a temperature from 2 °C to 10 °C.

Issue conditions:

According to the recipe

Packaging:

In ampoules on 1.5 ml in packs No. 3, No. 5 or No. 10.