Virus immunoglobulin of the person Epstein-Barre

General characteristics. Structure:

Active ingredients – kapsidny antibodies to a virus Epstein-Barre;

the stabilizer – glycine (glycine, the aminoacetic acid).

Main properties: drug is immunological the active protein fraction allocated from the blood plasma of the person cleared and concentrated by a fractionation method alcohol, which passed a stage of a virus inactivation solvent-detergentnym by method. Protein content in 1.0 ml of drug from 0:09 g to 0:11 g. Transparent or with insignificant opalescence, colourless or yellowish liquid. In the course of storage emergence of an insignificant deposit which disappears when stirring is possible. Drug contains antibodies to the Epstein-barrel virus. Drug does not contain preservative and antibiotics, in raw materials there are no antibodies to VICh-1, VICh-2, to a virus of hepatitis C and a surface antigen of a virus of hepatitis In (HBsAg).

Pharmacological properties:

The operating basis of drug are immunoglobulins, in particular the immunoglobulin G specific to the Epstein-barrel virus. Specific activity of drug is caused by virus neutralizing action of antibodies. Besides, immunoglobulin G, causes immunomodulatory effect, influencing different links of immune system of the person, and increases nonspecific resistance of an organism.

Indications to use:

Treatment of the diseases caused by the Epstein-barrel virus.

Route of administration and doses:

Immunoglobulin is entered intramusculary.

For treatment of diseases of the adult immunoglobulin is entered by 5 times with an interval of 48 hours in a dose of 4.5 ml (3 ampoules on 1.5 ml) on introduction. To children 3 years immunoglobulin are more senior enter 4-5 times in 48 hours in a dose of 3 ml (2 ampoules on 1.5 ml).

Features of use:

Administration of drug is intravenously forbidden!

There is no experience of use for children up to 3 years. To the persons suffering from immune general diseases (diseases of blood, connecting fabric nephrite, etc.), it is necessary to enter immunoglobulin against the background of basic therapy.

Use during pregnancy and feeding by a breast. Clinical experience of use of immunoglobulin indicates that it is not necessary to expect any harmful effects on mother and a fruit at pregnancy or on the newborn.

Immunoglobulin is emitted with breast milk and therefore can promote transfer of protective antibodys from mother to the child.

Side effects:

In rare instances local reactions in the form of a hyperemia and temperature increase to ^{37.5 0C} within the first days can develop. Allergic reactions are possible. In this connection the persons who received drug have to be under medical observation within 30 minutes after introduction.

Interaction with other medicines:

In complex therapy the acyclovir and ганцикловир is combined with other groups of drugs, including.

Contraindications:

Heavy allergic reactions to introduction of proteinaceous blood preparations of the person.

Overdose:

It was not studied.

Storage conditions:

In dry, protected from light, the place at a temperature from 2 °C to 8 °C. To store in the place, unavailable to children.

Issue conditions:

According to the recipe

Packaging:

In ampoules on 1.5 ml (1 dose) and 3.0 ml (2 doses) on 5 or 10 ampoules in a box with a corrugated insert or with a polymeric insert from a film polyvinyl chloride for placement and fixing of ampoules.