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Aminocapronic acid is antihemorrhagic and haemo static drug which possesses specific styptic action at the bleedings concerning increase in a fibrinolysis (process of dissolution of clots). This drug promotes reduction of permeability of capillaries, and also oppression of a fibrinolysis in general. Aminocapronic acid increases anti-toxic abilities of a liver, shows moderate antishock and antiallergic activity. Drug is capable to improve some indicators of specific and nonspecific protection at a SARS.
After use the maximum concentration of Aminocapronic acid in blood is observed in 2-3 hours. Linkng with proteins of plasma is practically absent. The main part of drug is removed by kidneys in an invariable look, and 10-15% biotransformirutsya in a liver. Accumulation of Aminocapronic acid happens only if there are disturbances of urinary function.
This drug is used when it is necessary to stop bleedings with the increased fibrinolitic activity of blood and fabrics which accompany surgical interventions and various morbid conditions. Thus, Aminocapronic acid is effective at bleedings after pancreas, lungs, prostate, thyroid gland operations, and also at premature placental detachment, acute pancreatitis, liver diseases.
This drug is produced in the form of powder for oral administration (1 bag corresponds to 1 g) and solution for infusions of 5%.
Powder is accepted inside in time or after food, washing down with sweet water or previously having dissolved in it. According to the instruction to Aminocapronic acid, the single dose of drug for intake is calculated as follows: 0,1 g multiply by the patient's weight in kilograms. The daily dose should be divided into 3-6 receptions, it usually corresponds to 5-24 g.
Aminocapronic acid to children is calculated by multiplication of 0,05 g of drug by the child's weight, however should not exceed 1 gram. The daily dose of drug depends on age of the child: to children till 1 year appoint 3 g, children are 2-6 years old – 3-6 bags; children of 7-10 years can accept drug in number of 6-9 g; 10 years – 10-15 g are more senior.
The daily dose of Aminocapronic acid to children is divided into 3-5 receptions.
In case of an acute hypofibrinogenemia Aminocapronic acid in the form of solution is entered in a dose of 100 ml in intravenously drop way, if necessary introduction repeats in 4 hours.
Aminocapronic acid in a nose is applied to prevention of flu that is caused by ability of drug to strengthen vessels in nasal bosoms, to reduce risk of bleedings and to increase coagulability of blood. This route of administration of drug is based on its antiedematous and antiallergic action, and also ability to reduce the number of allocations from a nose. Purpose of Aminocapronic acid in a nose allows to break interaction of an organism and a virus.
Use of 5% of solution of Aminocapronic acid according to the following scheme is recommended: 2-3 drops in a nose 4 times a day in the preventive purposes and every 3 hour at treatment. A course – 3-7 days. Aminocapronic acid in a nose is not contraindicated to pregnant women (on 3 drops 3 times a day), however before use it is necessary to consult at the doctor.
In the instruction to Aminocapronic acid the following negative effects are specified:
- arrhythmia, bradycardia, subendocardial hemorrhage, orthostatic hypotension;
- diarrhea and nausea; spasms, sonitus, dizziness, headaches;
- skin rash, acute renal failure, catarral phenomena of upper respiratory tracts.
Use of Aminocapronic acid is inadmissible at:
Storage of Aminocapronic acid has to happen in the dry place at a temperature which is not exceeding 250C. A period of validity – 2 years.
Name of drug
Aminocapronic acid solution of 5% 100 ml
The most rare disease – a disease the Kura. Only representatives of the tribe Faure in New Guinea are ill it. The patient dies of laughter. It is considered that eating of a human brain is an origin of a disease.
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