Klenbuterol

Klenbuterol – drug with adrenomimetichesky, broncholitic action.

Form of release and structure

Klenbuterol release in the form of syrup: colourless transparent liquid with a characteristic smell of raspberry (on 100 ml in dark glass bottles, on 1 bottle in a cardboard pack with a measured spoon in a set).

Is a part of 1 ml of syrup:

• Active agent: Klenbuterol – 0,001 mg (in the form of a hydrochloride);
• Auxiliary components: пропилпарагидроксибензоат – 0,05 mg, sorbitol – 280 mg, monohydrate of citric acid – 7 mg, глицерол – 200 mg, propylene glycol – 100 mg, a sodium citrate dihydrate – 5,8 mg, sodium benzoate – 1,2 mg, methylparahydroxybenzoate – 0,45 mg, butylparahydroxybenzoate – 0,05 mg, ethanol of 96% – 5 mg, crimson essence – 0,45 mg, the purified water – to 1 ml.

Indications to use

Klenbuterol appoint at treatment of bronchial asthma and chronic obstructive pulmonary disease (COPD).

Contraindications

• Myocardial infarction (in the acute period);
• Tachyarrhythmia;
• Hypertrophic subaortic stenosis;
• Thyrotoxicosis;
• Pheochromocytoma;
• Closed-angle glaucoma;
• Pregnancy (I and III trimester) and period of breastfeeding (lactation);
• Age up to 6 years;
• Hypersensitivity to drug components.

Klenbuterol appoint with care directly after the postponed myocardial infarction, and also the patient with disturbances of a cordial rhythm, a renal and liver failure, myocarditis, a hypopotassemia, defects of the mitral valve, unstable or noncompensated diabetes.

Route of administration and dosage

Klenbuterol accept inside.

The daily dose is defined by age:

• Children of 6-12 years (with the body weight of 22-35 kg) – 0,015 mg;
• Adults and children of 12 years: 0,02-0,04 mg.

Frequency rate of reception – 2 times a day.

Maintenance dose – on 0,01 mg 2 times a day.

On average Klenbuterol apply 2-3 days (before removal of acute symptoms of a disease).

Duration of the supporting treatment – up to 7 days. Longer therapy is possible after consultation with the doctor.

Side effects

At Klenbuterol's use the following side effects can develop:

• Cardiovascular system: increase or lowering of arterial pressure, anginapny pains, tachycardia, ventricular premature ventricular contraction;
• Central nervous system: headache, concern;
• Muscular system: small tremor of muscles;
• Urinogenital system: disturbance of an urination;
• Circulatory system: hypoglycemia, thrombocytopenia;
• Digestive tract: diarrhea, gastritis, nausea, dryness in a mouth;
• Mucous membranes and skin: face edema, skin rash, small tortoiseshell.

These side reactions, as a rule, take place within 7-14 days without the therapy termination.

Special instructions

So-called parabens are Klenbuterol's part as auxiliary components: пропилпарагидроксибензоат and methylparahydroxybenzoate which can lead to development of a small tortoiseshell and contact dermatitis (allergic reactions of the slowed-down type). Emergence of allergic reactions of immediate type is in rare instances possible (bronchospasm).

Glitserol who is a part of syrup in high doses can cause irritation of a stomach, diarrhea and a headache.

Contains in 1 ml of Klenbuterol 5 mg of ethanol of 96% that constitutes danger to patients with alcoholism, liver diseases, epilepsy, diseases or damages of a brain, and also for children and pregnant women.

Because of existence in composition of drug of sorbitol, it should not be accepted the patient with inborn intolerance of fructose.

Klenbuterol can strengthen effect of other medicines.

In the first days of therapy drug can cause concern and a small tremor that demands the increased care during the driving and work with the equipment.

Medicinal interaction

At simultaneous use of Klenbuterol with some medicines there can be undesirable effects:

• Beta adrenoblockers: suppression of action of Klenbuterol, risk of development of a bronchospasm;
• Beta-adrenergic agonists, theophylline and anticholinergics: strengthening of their action and side effects;
• Hypoglycemic medicines: reduction of their action;
• The halogenated hydrocarbons for an anesthesia (when carrying out manipulations and interventions): increase in risk of development of arrhythmias;
• Monoamine oxidase inhibitors (tricyclic antidepressants): disturbance of a cordial rhythm.

Perhaps simultaneous use of Klenbuterol with cardiac glycosides and diuretics, but when carrying out periodic control of serumal electrolytes.

Terms and storage conditions

To store in the place, unavailable to children, at a temperature up to 25 °C.

Period of validity – 3 years.