Glucagon
Application instruction:
Glucagon – pancreas hormone with diagnostic and hyper glycemic action.
Form of release and structure
The glucagon is released in the form of lyophilisate for preparation of solution for injections (in bottles on 1 mg, complete with solvent).
Active agent is a part of 1 bottle: a glucagon – 1 mg.
Indications to use
- Hypoglycemia;
- Radiological diagnosis of digestive tract.
Contraindications
- Insuloma;
- Pheochromocytoma;
- Hypersensitivity to drug components.
To the feeding and pregnant women use of the Glucagon is possible only according to strict indications.
Route of administration and dosage
The glucagon is applied subcutaneously, intramusculary and intravenously.
At a hypoglycemia usually appoint 1 mg in a dose. Children with body weight less than 20 kg should apply the Glucagon at the rate of 0,02-0,03 mg/kg.
As supportive diagnostic application the drug is administered intramusculary or intravenously in a dose from 0,25 to 2 mg.
Side effects
During therapy development of such side effects is possible: vomiting, nausea, allergic reactions (hypotension, respiratory distress syndrome, small tortoiseshell).
Special instructions
The glucagon should be applied with care the patient with suspicion on a pheochromocytoma or an insuloma.
At use of the Glucagon it is necessary to consider that it is inefficient at a chronic hypoglycemia, insufficiency of adrenal glands, and also at the patients who are on a reducing diet as influences only in the presence in a glycogen liver.
At the patients accepting beta adrenoblockers at introduction of the Glucagon development of the expressed tachycardia and arterial hypertension is possible.
Medicinal interaction
Phenytoinum inhibits the insulin release caused by action of the Glucagon.
The glucagon can strengthen effect of peroral anticoagulants.
Terms and storage conditions
To store in protected from light, the place, dry, unavailable to children, at a temperature of 15-30 °C.
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