- Agammaglobulinemia symptoms
- Agammaglobulinemia reasons
- Treatment of the Agammaglobulinemia
Agammaglobulinemia (a synonym a syndrome of deficit of antibodies) — absence or sharp decrease in content of gamma-globulins in a blood plasma. At the same time there is impossible a development of necessary quantity of antibodies in this connection patients with an agammaglobulinemia are extremely subject to infectious diseases.
Clinically the agammaglobulinemia is characterized by predisposition to bacterial infections at the normal resilience against a viral infection. Infectious diseases at an agammaglobulinemia proceed is long, with frequent aggravations and heavy complications. The diagnosis is established by identification of low level of gamma-globulins at a plasma electrophoresis. The forecast is adverse.
Distinguish the hereditary and acquired agammaglobulinemia. The hereditary agammaglobulinemia — a rare disease, happens at boys (usually comes to light aged up to 6 years); it is connected with an underdevelopment of lymphoid and plasmatic fabric and loss by an organism of ability of synthesis of gamma-globulins. The acquired agammaglobulinemia occurs at people of both sexes aged from 7 up to 70 years; in some cases the disease is a consequence of the postponed serious infectious diseases or arises at malignant new growths of the lymphoid device (a chronic lymphoid leukosis, etc.), nefroza, etc.
Treatment of the Agammaglobulinemia:
Treatment is carried out under control of the doctor: administration of gamma-globulin once a month on 0,1 g on 1 kg of body weight intramusculary; hemotransfusion.