Stimol

General characteristics. Structure:

Active agent: 50% solution of malate of citrulline - 2 g

Excipients: fragrance from natural orange sangria; strong solution of a hydroxide of sodium; the distilled water.

Pharmacological properties:

The drug used at asthenic states. Has all-tonic effect, and also promotes a liver detoxication.
Citrulline — the amino acid participating in the cycle of neutralization of the ammonia which is formed as a result of disintegration of nitrogen-containing connections proceeding in a liver. In a liver urea is formed of ammonia. Citrulline is built in an urea cycle, increases removal of ions of ammonium.
Malate is involved in a tricarbonic acid cycle and a gluconeogenesis, reduces concentration of a lactate in blood, contributes to normalization of a metabolism, activates nonspecific protective factors of an organism.
In the beginning

Pharmacokinetics. Absorption. After intake drug is quickly soaked up from a GIT. Cmax in a blood plasma is reached on average in 50 min. It is quickly brought out of plasma. In 6 h concentration in plasma is close to physiological.

Metabolism and removal
Since active component joins in processes of cellular metabolism, only its small amounts are found in urine.

Indications to use:

STIMOL is applied at a symptomatic treatment of a functional adynamy, an asthenic syndrome, overfatigue, the increased fatigue, during recovery after the postponed diseases. As as a part of STIMOLA there is no sugar, it can be accepted a sick diabetes mellitus.

Route of administration and doses:

Adults and elderly people: contents of 3 bags or 3 ampoules in day.
Children since 5 years: contents of 2 bags or 2 ampoules in day.
STIMOL should be accepted during food, mixing with water or the sweetened drink. Course of administration of drug of 10-12 days. Repeated courses are possible after a break (1-3 months) or according to the recommendation of the doctor.

Features of use:

Each bag or ampoule contains about 30 mg of sodium. It should be taken into account to the patients who are on an electrolyte-deficient diet. In case of doubts consult to the attending physician.

Side effects:

In certain cases in an initiation of treatment there can be passing pains in a stomach. Report to the doctor about the undesirable reactions which are not mentioned in this instruction if they arise at reception of this drug.

Interaction with other medicines:

To avoid possible interactions with other drugs, it is necessary to inform your doctor on what medicine you take now systematically.

Contraindications:

Peptic ulcer in an aggravation stage, the increased individual sensitivity to drug.

Overdose:

There are no data.

Storage conditions:

To store at the room temperature of 15-25 °C, in the place, unavailable to children.

Issue conditions:

Without recipe

Packaging:

Bags from a paper polietileno-allyuminiyevogo of a complex on 10 ml everyone.
Glass ampoules on 10 ml everyone.
In a cardboard box of 18 bags or 18 ampoules and application instruction.