Drops are nasal: almost transparent solution from colourless till slightly yellow color (on 5 or 10 ml in glass bottles of dark color with a cover pipette, in a cardboard pack 1 bottle);
Spray of nasal 0,05%: transparent solution from weak-yellow color to almost colourless (on 10 ml in a polyethylene bottle with the sprayer, in a cardboard pack 1 bottle).

Active ingredient of Nazivin – oxymetazoline a hydrochloride, in 1 ml:

Drops: 0,1 mg, 0,25 mg or 0,5 mg;
Spray: 0,5 mg.

Auxiliary components:

Drops: a benzalkoniya chloride (50% solution), hydroxide 1M sodium solution, sodium dihydrophosphate a dihydrate, dinatrium эдетат a dihydrate, sodium hydrophosphate a dihydrate, the water purified;
Spray: a benzalkoniya chloride (50% solution), citrate sodium a dihydrate, citric acid monohydrate, глицерол (85%), the water purified.

Indications to use

Vasculomotor rhinitis;
Rhinitis at acute respiratory diseases;
Allergic rhinitis;
Eustachitis, inflammation of adnexal bosoms of a nasal cavity, average otitis (for recovery of a drainage;
Elimination of hypostasis in the nasal courses before conducting diagnostic testings.

Contraindications

Age up to 6 years (for drug of 0,05% of concentration);
Closed-angle glaucoma;
Atrophic rhinitis;
Hypersensitivity to drug components.

With care it is necessary to apply Nazivin in combination with the monoamine oxidase inhibitors (MAO) and other means promoting increase in the arterial pressure (AP) and also during the next 10 days after their cancellation; at heavy cardiovascular pathologies (including arterial hypertension and stenocardia), the increased intraocular pressure, a diabetes mellitus, a thyrotoxicosis; during pregnancy and breastfeeding.

It is necessary to observe strictly the concentration of drug intended for different age categories.

Besides, drops in concentration of 0,025% cannot be applied to treatment of children aged till 1 year.

Route of administration and dosage

Nazivin apply intranazalno, digging in or injecting means into each nasal course on 2-3 times a day within 3-5 days.

The recommended one-time dosing:

Drops: on 1-2 drops;
Spray: on 1 injection.

Concentration of drops has age restrictions:

To patients 6 years are more senior appoint 0,05% (in 1 ml – 0,5 mg);
To children of 1-6 years – 0,025% (in 1 ml – 0,25 mg);
To children till 1 year – 0,01% of a drop (in 1 ml – 0,1 ml).

To babies aged up to 4 weeks appoint on 1 drop in each nasal course 2-3 times a day.

The bottle with drops of 0,01% has the graduated pipette which provides dosing accuracy, for example, at purpose of 1 drop, the pipette is filled with solution to a mark 1.

Efficiency of the following procedure is proved: 1-2 drops (depending on age) 0,01% of solution need to be applied on a cotton plug and to wipe the nasal courses.

It is possible to exceed the recommended doses only on doctor's orders.

Side effects

Nervous system: seldom – fatigue, concern, sleeplessness, a headache;
Local reactions: sometimes – sneezing, burning sensation and a xeromycteria; in rare instances – feeling of a congestion of a nose after completion of effect of drug (reactive hyperemia);
Cardiovascular system: at repeated disturbance of the mode of dosing development of tachycardia, arterial hypertension is possible;
Alimentary system: seldom – nausea;
Others: the long continuous period of treatment by vasoconstrictive drugs can cause an atrophy, a tachyphylaxis and medicamentous rhinitis in the form of returnable hypostasis of mucous membranes of a nose.

Special instructions

Nazivin it is impossible to use a long time, it is necessary to avoid drug overdose, especially at treatment of children.

Influence of drug on ability of the patient to control of vehicles and mechanisms can be shown after long therapy in high doses as it is impossible to exclude emergence of side effects of drug from nervous and/or cardiovascular system.