Salofalk

Salofalk – the anti-inflammatory drug which is applied to treatment of diseases of intestines.

Pharmacological action

Salofalk has effect directly on mucous intestines therefore it is considered local anti-inflammatory drug.

Active ingredient of medicine – месалазин which, except antiinflammatory shows also antioxidant property.

Release form

Salofalk release in the form of kishechnorastvorimy tablets and granules, suspension and rectal candles.

Direct analogs of Salofalk on active ingredient – drugs Mesalazin, Mesakol, Salozinal, Pentasa, Salazopiridazin.

Indications to use

Salofalk and Salofalk's analogs appoint for treatment of a disease Krone – a chronic disease of a small intestine, and also nonspecific ulcer colitis.

Judging by responses, Salofalk well proved as prophylactic: regular use of drug gives the chance to avoid an exacerbation of the specified diseases.

Salofalk's instruction: route of administration

Pill Salofalk is taken inside: adults are recommended to accept 1500 mg a day. If the inflammation passes in a severe form, it is possible to increase a dosage to 3-4 g. It is possible to continue treatment by tablets 2-3 months.

For prevention of a recurrence of an inflammation accept Salofalk 1500 mg a day. In certain cases prevention lasts several years.

Children weighing up to 40 kg are given drug in a dosage of 750 mg in knocks. If the weight of the child exceeds 40 kg, it can give 1500 mg a day.

As preventive treatment to children appoint 750 mg a day.

Pill is recommended to be taken whole, without chewing, washing down with a large amount of water.

Granules Salofalk according to the instruction at an exacerbation of ulcer colitis accept 1500-3000 mg a day. For the supporting treatment appoint 1500 mg a day.

To children after 6 l. at an aggravation of an inflammation of intestines give drug in a dosage of 30-50 mg/kg. As the supporting treatment to children appoint 5-30 mg/kg.

The acute stage of ulcer colitis passes usually in 8-12 weeks, after that it is possible to reduce a dosage to 1,5 g. Children weighing up to 40 kg can appoint granules in the dosage reduced twice for adults. Children whose weight exceeds 40 kg can appoint drug in the same dose, as the adult.

Granules Salofalk cannot be chewed also.

Rectal candles Salofalk apply three times a day – enter into a rectum. A necessary daily dosage – 1500 mg. If a hard case, it is possible to double a dosage. At long therapy appoint to enter 750 mg a day. The acute inflammation, judging by reviews of Salofalk candles, passes through 8-12 weeks.

Suspension use in a dosage 60 g a day. Enter means into a rectum by means of an enema, for the night. Intestines should be cleared previously.

Side effects of Salofalk

Salofalk can cause fever, bronchospasms, urticaria and an itch, myocarditis, a pericardis, anemia, a neutropenia, an agranulocytosis, diarrhea, acute pancreatitis, hepatitis, a meteorism, nausea, an abdominal pain, intersticial nephrite, increase in activity of enzymes of a liver.

There are reviews of Salofalka indicating that drug can provoke baldness, dizziness, a headache.

At overdose there is a drowsiness, nausea, a gastralgia, vomiting, weakness. To the patient at overdose wash out a stomach, give laxative, carry out necessary symptomatic therapy, in certain cases – an artificial diuresis.

Contraindications

Salofalk according to the instruction do not appoint to children up to two years, to patients with heavy disturbances of work of kidneys, a liver, with hemorrhagic diathesis, blood diseases, a round ulcer of a GIT, with hypersensitivity to salicylates, a mesalazin and other components of medicine.

Salofalk and analogs of drug during the breastfeeding, pregnancy is not recommended to apply.

At prescription of medicine consider that Salofalk can strengthen effect of anticoagulants that, in turn, can become the reason of gastrointestinal bleeding.

It is undesirable to combine drug with glucocorticosteroids, besides it is established what месалазин can reduce efficiency of furosemide, rifampicin, Spironolactonum.