Main > Drugs> Simgal

Simgal

The prices in Internet drugstores:

from 217 rub.

Simgal – hypolipidemic medicine.

Structure and form of release of Simgal

Simgal produce in the form of tablets, coated, containing active ingredient – симвастатин 10, 20 or 40 mg.Симгал в упаковке

Auxiliary components: monohydrate of lactose, microcrystallic cellulose, magnesium stearate, prezhelatinizirovanny starch, ascorbic acid, monohydrate of citric acid, butylhydroxyanisole.

In blisters on 7 and 14 tablets.

Simgal's analogs are the following medicines: Allesta, Vazilip, Zovatin, Zosta, Simvakard, Simvalimit, Simvastatin.

Pharmacological action

Hypolipidemic medicine, the GMG-KOA-reduktazy inhibitor extracted from Aspergillus terreus fermentation product in the synthetic way.

Simgal according to the instruction causes decrease in maintenance of LPONP, LPNP, TG in a blood plasma, and also general Hs (in cases of the mixed lipidemia, a heterozygous single and family form of a hypercholesterolemia when the increased content of cholesterol in blood is unsafe for an organism).

According to Simgal reduces LPVP/LPNP ratio, general Hs/LPVP and increases concentration of LPVP.

Simgal's effect or his analogs is shown after two weeks of use. The maximum therapeutic effect is reached after 1-1,5 months of use of drug.

Simgal's action according to reviews remains throughout all treatment. After drug withdrawal the level of Hs gradually becomes former.

Indications to Simgal's use

According to the instruction Simgal is shown:

  • at the combined hypercholesterolemia and the gipertriglitseridemiya which are not giving in to adjustment by special diets and exercise stresses;
  • at primary hypercholesterolemia in case of inefficiency of a hypocholesteric diet and other non-drug means at patients with tendency to developing of coronary atherosclerosis.

Appoint Simgal according to the instruction at an ischemic heart disease:

  • for reduction of risk of death;
  • for the purpose of prevention of a myocardial infarction;
  • for the purpose of reduction of risk of procedures of a revaskulyation;
  • for delay of progressing of atherosclerosis.

Drug or Simgal's analogs at a cerebrovascular disease is effective (at tranzitorny ischemic disturbances and a stroke).

Contraindications

According to the instruction Simgal is contraindicated in the following cases:

  • pregnancy and breastfeeding;
  • active phase of diseases of a liver, permanent increase in activity of liver enzymes of the obscure character;
  • diseases of skeletal muscles (myopathy);
  • age up to 18 years;
  • hypersensitivity to acting or to other components of drug.

According to responses Simgal it is necessary to appoint with care:

  • in case of an alcohol abuse;
  • to the patients after organ transplantation receiving treatment by immunodepressants;
  • at arterial hypotension;
  • at disturbances of water and electrolytic balance;
  • at the expressed endocrine and metabolic disturbances;
  • at infectious diseases of a heavy current;
  • at injuries and surgical interventions;
  • at epilepsy;
  • to patients with the lowered tone of skeletal muscles of the obscure character.

Routes of administration of Simgal and mode of dosing

Before an initiation of treatment the patient is recommended to appoint a hypocholesteric diet which needs to be observed throughout all course of treatment drug or Simgal's analog.

As a rule, according to the instruction Simgal accept inside once a day, it is more preferable in the evening, washing down a tablet with water.

At treatment of a hypercholesterolemia the recommended dosage of drug varies from 10 to 80 mg once a day. The initial dosage makes 10 mg. It is necessary to carry out correction of a dose at an interval of one month. At most of patients the optimum effect is reached at Simgal's reception in a dosage of 20 mg a day.Симгал в блистерах

In case of a homozygous hereditary hypercholesterolemia the recommended dosage of drug or Simgal's analog makes 40 mg once a day or 80 mg divided into three receptions.

At coronary heart disease or at risk of its development the dosage of drug makes 20-40 mg once a day.

In case the patient combines drug with verapamil or Amiodaronum, the maximum daily dosage of Simgal should not exceed 20 mg.

Side effects

As a rule, Simgal according to reviews, at use in the recommended dosages, is well had by patients. The following by-effects from various systems of life activity of an organism are possible:

  • vomiting, nausea, diarrhea or lock, abdominal pains, hepatitis, meteorism, increase in activity of hepatic transaminases, meteorism, pancreatitis;
  • sleeplessness, dizziness, headache, asthenic syndrome, vagueness of sight, paresthesia, peripheral neuropathy, disturbance of flavoring feelings, spasms;
  • weakness, myotonia, myopathy, mialgiya, рабдомиолиз;
  • acute renal failure;
  • photosensitization, itch, skin rash, alopecia, dermatomyositis;
  • rheumatic polimialgiya, Quincke's disease, fever, volchanochnopodobny syndrome, dermahemia, eosinophilia, small tortoiseshell, increase in SOE;
  • anemia, thrombocytopenia;
  • asthma, inflows, decrease in a potentiality, heartbeat.

Simgal's use during pregnancy and a lactation

According to the instruction Simgal is contraindicated during pregnancy and a lactation.

Several reviews of Simgala testimonial of development of anomalies in newborns whose mothers accepted drug arrived. Therefore the women of childbearing age accepting drug or Simgal's analogs have to avoid conception.

Any data on release of active ingredient of Simgal with breast milk are absent. However it is necessary to consider that the majority of medicines are distinguished with breast milk of mother therefore use of drug during breastfeeding is not recommended.

Storage conditions

Store drug in the dry cool place not longer than four years.

The prices in Internet drugstores:

Name of drug

Price

Drugstore

Simgal of a tablet 10 of mg of 28 pieces

217 rub.

Аптека вер.ру, ОООApteka вер.ру, LLC

Simgal of a tablet 20 of mg of 28 pieces

285 rub.

Аптека вер.ру, ОООApteka вер.ру, LLC

Simgal тбл п/пл/о 10 mg No. 28, Teva Czech Enterprises of neuter of the lake.

288 rub.

Сеть московских аптек ИФКNetwork of the Moscow drugstores of IFC

Simgal тбл п / about 20 mg No. 28, IVAX Pharmaceuticals s.r.o.

322 rub.

Сеть московских аптек ИФКNetwork of the Moscow drugstores of IFC

Simgal тбл п/пл/о 40 mg No. 28, Teva Czech Enterprises of neuter of the lake.

588 rub.

Сеть московских аптек ИФКNetwork of the Moscow drugstores of IFC

Simgal of a tablet 10 of mg of 84 pieces

591 rub.

Аптека вер.ру, ОООApteka вер.ру, LLC

Simgal of a tablet 40 of mg of 28 pieces

620 rub.

Аптека вер.ру, ОООApteka вер.ру, LLC
 
 
Whether you know that:

During sneezing our organism completely stops working. Even heart stops.