Adrenal insufficiency

Description:

Adrenal insufficiency (insufficiency of bark of adrenal glands, hypocorticoidism) - the clinical syndrome caused by insufficient secretion of hormones of bark of an adrenal gland as a result of disturbance of functioning of one or several links гипоталамо - pituitary and adrenal system. Adrenal insufficiency is subdivided into primary, being result destructions of the bark of adrenal glands, and secondary (gipotalamo-pituitary), arising owing to insufficiency secretions of AKTG by an adenohypophysis. In clinical practice primary chronic adrenal insufficiency (95% of cases) most often meets. The disease caused by destructive process in adrenal glands for the first time was described in 1855 by the English doctor Thomas Addison (1793-1860). Primary hypocorticoidism of an autoimmune and tubercular etiology is designated as Addison's disease.

Symptoms of Adrenal insufficiency:

The clinical picture of a secondary hypocorticoidism is distinguished by absence of the hyperpegmentation and symptomatology connected with deficit of Aldosteronum (arterial hypotonia, addiction to salty food, dyspepsia). Into the forefront such low-specific symptoms as the general weakness and attacks of a hypoglycemia which are described how feeling sick episodes in several hours after food act.

Reasons of Adrenal insufficiency:

Reasons of a secondary hypocorticoidism. Because products of Aldosteronum bark of adrenal glands occur practically irrespective of effects of AKTG, at a secondary hypocorticoidism owing to a lack of AKTG deficit only of one cortisol develops, and products of Aldosteronum remain. It defines the fact that the secondary hypocorticoidism has rather easier current in comparison with primary.

Treatment of Adrenal insufficiency:

Feature of replacement therapy at a secondary hypocorticoidism consists in lack of need of purpose of a fludrokortizon, except for separate cases of the expressed hypotonia.