Lymphoma of a thyroid gland

Description:

The lymphoma center in tissue of a thyroid gland is not the only thing in a body of the person. The lymphoma is regarded as the disease connected with multiple defeat of bodies of lymphatic system malignant process.

Pathogeny:

Primary lymphoma arising in a thyroid gland a rare tumor, which is found 2-4% among all malignancies of a thyroid gland. Secondary involvement of a thyroid gland, at all types of lymphoma and leukemias, more frequent, is also shown at generalization of process to 10% of cases. Middle age is presented by people of advanced age (60-70 years), a ratio of women with men 3: 1. The cases which are found at young age (up to 40 years) are extremely rare. At 83% of patients with a lymph of a thyroid gland, existence before a thyroiditis of Hashimoto confirmed with existence of antibodies to a thyroid gland and a histologic research is noted. Primary lymphoma of a thyroid gland, usually happens B-cellular type, and more rare T-cellular.

Stadirovany diseases.

At the moment classify lymphoma by stages on the Ann Arbor system.

At distribution of a lymphoma in a thyroid gland the stadirovaniye is carried out as follows:

IE stage at patients with primary lymphoma limited in a thyroid gland.
IIE stage a tumor is limited by a thyroid gland and regional lymph nodes of a neck.
stages III and IV more common forms of a disease, involve in process other bodies and systems, including the gastrointestinal treatise, marrow, lungs, a liver, a spleen.
All stages are subdivided on:

And - without loss of body weight / fever / night sweat
In - with loss by body weight / fever / night then

Symptoms of a lymphoma of a thyroid gland:

Most often patients complain of emergence of a tumor on a neck, note causeless weight loss, night pouring sweats, change of a voice, in the started cases disturbance of passing of food (even liquid), breath difficulties.

Diagnosis:

At survey, the enlargement of the thyroid gland most often seen approximately and cervical lymph nodes, meets in 50% of cases. As a result of bystry increase in a tumor of a thyroid gland symptoms of a prelum of surrounding bodies and fabrics appear. Carry a dysphagy, an asthma, an osiplost to these symptoms. The diagnosis is confirmed on the basis of a fine-needle aspiration biopsy and a cytologic research. It is also necessary the subsequent carrying out a biopsy and an immunohistochemical research since B - a macrocellular lymphoma is similar on a histologic structure to undifferentiated cancer of a thyroid gland and a lymphoma of MALT. To additional methods of inspection include full clinical, biochemical blood tests (focus attention to a lactic dehydrogenase and uric acid) and analyses on function of a thyroid gland, their credits often rise. Also carry out the computer tomogram of a neck, thorax, abdominal cavity, small pelvis, carry out aspiration of marrow and its trepan a biopsy.

Treatment of a lymphoma of a thyroid gland:

Treatment of a lymphoma thyroid zhelezyprovoditsya with use of chemotherapy (sometimes - by the combined use himio-and radiation therapy).

Surgical treatment at these tumors does not make neither sense in the performance, nor need. At the combined treatment of PHT + DLT is noted increase in bezretsidivny five-year survival up to 90% in this connection, this scheme of treatment became a standard rule in most institutions.