Омикс tab.0,4 No. 10, 30

General characteristics. Structure:

Active ingredient: tamsulozina of a hydrochloride; 1 capsule contains a tamsulozin of a hydrochloride of 0,4 mg; excipients: cellulose microcrystallic, колликоат MAY 30 DP, gipromelloz (gidroksipropilmetiltsellyuloz), propylene glycol, talc, magnesium stearate, sodium lauryl sulfate.

Pharmacological properties:

Lowers a tone of smooth muscles of a prostate, neck of a bladder and a prostatic part of an urethra, improving urine outflow. At the same time the symptoms of obstruction and irritation connected with a high-quality prostatauxe decrease. The therapeutic effect develops in two weeks after an initiation of treatment. Thanks to high selectivity, does not cause clinically significant decrease in system arterial pressure both in patients with hypertensia, and in patients with normal initial arterial pressure.
After intake it is quickly and completely soaked up in digestive tract. Tamsulozin is not exposed to effect of "the first passing" through a liver and biotransformirutsya slowly in a liver with formation pharmacological of active metabolites. It is removed by kidneys, 9% of a dose are allocated in not changed look.

Indications to use:

Symptomatic treatment of functional symptoms at a benign hyperplasia of a prostate.

Route of administration and doses:

Inside, without chewing, after a breakfast, washing down with enough water, on 1 capsule (0,4 mg). The course of treatment is defined by the doctor.

Features of use:

With care apply at predisposition to orthostatic hypotension, the expressed abnormal liver functions and clearance of creatinine (Cl) it is lower than 10 ml/min. At emergence of symptoms of orthostatic hypotension (dizziness, weakness) of the patient it is recommended to seat or lay.
Before an initiation of treatment it is necessary to verify the diagnosis.

It is necessary to adhere to care when working, connected with high concentration of attention, and at control of vehicles (in connection with possible developing of dizziness).

Side effects:

From cardiovascular system: seldom – dizziness, orthostatic hypotension, a heart consciousness.
From TsNS: sometimes – a headache, an adynamy.
From a reproductive system: seldom – a retrograde ejaculation.
From digestive tract: seldom – nausea, vomiting, diarrhea, a lock.
Allergic reactions: sometimes – skin rash, an itch, a Quincke's disease.

Interaction with other medicines:

At simultaneous use with Cimetidinum perhaps some increase in concentration of a tamsulozin in a blood plasma, and with furosemide – decrease in concentration, however it does not demand changes of a drug dosing. Diclofenac and indirect anticoagulants (warfarin) can increase the speed of elimination of a tamsulozin several. Co-administration with others α1-адренорецепторами can lead to the expressed strengthening of hypotensive effect.

Contraindications:

The increased individual sensitivity, orthostatic hypotension in the anamnesis, a heavy liver and/or renal failure. Children's age.

Overdose:

In case of any undesirable effects it is necessary to suspend temporarily use of drug and to see urgently a doctor. Purpose of kardiotropny therapy is recommended. If symptoms do not disappear, it is necessary to administer objemzameshchayushchy solutions or the vasoconstrictive drugs. For the prevention of further absorption of drug the gastric lavage, purpose of absorbent carbon or osmotic laxative is possible.

Storage conditions:

It is not necessary to use drug after the expiry date specified on packaging. In the dry, protected from light place at a temperature from 15 °C to 25 °C.

Period of validity - 3 years

Issue conditions:

According to the recipe

Packaging:

On 10 capsules in a blister strip packaging. 1 or 3 blister strip packagings in a pack from a cardboard.