Венитан® cream

General characteristics. Structure:

Active ingredient: 1 g of cream contains 50 mg of extract from seeds of a horse-chestnut which part 20% of an estsin are that answers 1% of an estsin in cream on a hydrophilic basis; excipients: едитат sodium, sorbic acid, a glitserola monostearate, white soft paraffin, light mineral oil, cetostearyl alcohol, kaprilovy/kaprovy триглицерол, propylene glycol, silicon dioxide, a gidroksiyetiltselyuloz, methylpolysiloxane, polyoxyethylene 20, sorbitan monopalmitate, the purified water.

Pharmacological properties:

Venitan contains cream β-эсцин. Estsin is a natural mix of the triterpenovy saponins received from horse-chestnut seeds (Aesculus hippocastanum L.), who have antiedematous, venomotor properties and show antiinflammatory activity. Besides, эсцин operates on the initial stage of inflammatory process connected with the increased membrane and capillary permeability and products of exudate in adjacent fabrics.
Venitan cream renders antiserotoninovy and antihistaminic effect.
Estsin inhibits activity prostaglandin-sintetazy. This enzyme is necessary for formation of prostaglandins which play an important role in the inflammation mechanism.
Estsin prevents decrease in content of ATP in endothelial cells and increases activity of a phospholipase of A2, enzyme which is responsible for release of predecessors of mediators of an inflammation.
Estsin lowers activity of the lizosomalny enzymes splitting the proteoglycans which are contained in walls of capillaries. It increases capillary resistance, reduces their permeability, reducing thus amount of exudate and formation of hypostases.
Venitan cream is intended for simplification of such phenomena as hypostasis, heavy feeling and fatigue in the legs caused venostazy the lower extremities. It is good addition to compression therapy (an elastic bandage, elastic stockings, bandages). Besides, cream reduces hypostasis and accelerates a resorption of hematomas from blows, and also owing to infusions or injections.

Indications to use:

The hypostases of legs and pain connected with venous insufficiency; varicosity; posttraumatic hematomas and hematomas after injections and infusions.

Route of administration and doses:

To apply a thin film of cream on the damaged site of skin and around it 2–3 times a day.
It is not necessary to rub.
At a varicose disease of veins simultaneous use of an elastic bandage or elastic stockings is recommended.
Duration of treatment depends on expressiveness of medical effect. If after 14 days of therapy of improvement does not come, it is necessary to see a doctor. Therapy can be continued to 8 weeks or before reduction of expressiveness of symptoms.

Features of use:

Not to apply cream on the inflamed skin, open wounds and mucous membranes. Not to rub when drawing. At sudden emergence of the expressed symptoms of venous insufficiency (hypostasis, skin discoloration, feeling of tension and pain), especially on one extremity, it is necessary to exclude a vein thrombosis of the lower extremities.
Use during pregnancy or feeding by a breast. Venitan cream can be applied during pregnancy and feeding by a breast, previously having consulted with the doctor.
Ability to influence speed of response at control of vehicles or other mechanisms. Does not influence.
Children. Experience of use of drug for children is not enough therefore it is not recommended to apply it at patients of this age category.

Side effects:

Hypersensitivity reactions (contact dermatitis, irritation of skin) are possible. In case of such reactions it is necessary to stop use of drug and to see a doctor.
Cream contains propylene glycol which can cause irritation of skin, sorbic acid (E200), cetostearyl alcohol which can cause local skin reactions (for example contact dermatitis).

Interaction with other medicines:

Are unknown. It is not recommended to apply cream on one site of skin together with other means to topical administration.

Contraindications:

Hypersensitivity to drug components.

Overdose:

There are no messages on overdose.

Storage conditions:

Do not accept drug after the termination of date of a period of validity. A period of storage - 2 years. Storage conditions. At a temperature not above 25 °C. To store in the place, unavailable to children!

Issue conditions:

Without recipe

Packaging:

Cream in tubas on 50 g.