Hartman solution

General characteristics. Structure:

Active ingredient: 0,438 g of Calcii chloridum, 0,373 g of potassium of chloride, 6,02 g of sodium of chloride, 6,276 g of solution of sodium of a lactate.

Excipients: acid solution hydrochloric 1M - рН 5,5-6,3, water for injections.

Regidratiruyushchy means, has disintoxication effect.

Pharmacological properties:

Pharmacodynamics. Normalizes an acid-base state. Fills shortage of volume of the circulating blood, stabilizes water and electrolytic composition of blood. The lactate is metabolized in an organism in bicarbonate therefore solution possesses the alkalinizing action. Solution is close to isotonic, osmolarity - 278 ¼Äß¼«½ý/kg.

Indications to use:

Hypovolemia, isotonic dehydration, metabolic acidosis.

Route of administration and doses:

In/in kapelno with a speed of 60 thaws/min. At medical emergencies – 180 thaws/min., in the volume depending on a condition of the patient.

The adult an average daily dose - 1 l, to children - 20-30 ml/kg.

The maximum daily dose – 2,5 l.

Features of use:

Use at pregnancy and during breastfeeding – use of drug is admissible if the expected advantage for mother exceeds potential risk for a fruit. In the period of a lactation it is necessary to refrain from feeding by a breast.

It is necessary to carry out regular blood test for definition of electrolytes, рН and rso2,  the volume of the circulating blood.

Side effects:

Thrombophlebitis, hypervolemia, overhydratation, hyperchloremia, uneasiness, allergic reactions.

Interaction with other medicines:

NPVP, androgens, anabolic steroids, estrogen, corticotropin, mineralokortikoida, vazodilator, ganglioblokator increase risk of development of a hypernatremia.

At reception with kaliysberegayushchy diuretics, drugs of KA + the risk of development of a hyperpotassemia amplifies.

Alkalinizes urine and slows down removal of the HP having alkali reaction.

Accelerates removal of Li + and salicylates.

Contraindications:

Hypersensitivity, hypervolemia, hypertensive dehydration, giperkalemiya, hypernatremia, arterial hypertension, heart and/or renal failure, hyperchloremia, alkalosis, liver failure (decrease in formation of a hydrocarbonate from a lactate), a hyper lactacidemia.

With care - respiratory insufficiency, an acute degidradatation, simultaneous treatment by glucocorticosteroid means.

Storage conditions:

Period of storage 2 years. Not to use after the period of validity specified on packaging In the place, dry, unavailable to children, at a temperature not above 25 °C.

Issue conditions:

According to the recipe

Packaging:

On 200 ml or 400 ml in bottles glass for blood, infusional and transinfusional drugs, corked by rubber bungs and rolled by metal caps. Each bottle with the application instruction is placed in a pack from a cardboard. On 28 bottles on 200 ml or on 15 bottles on 400 ml from 10-15 by application instructions pack boxes from a cardboard (for hospitals).